WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0004423 iduronate-2-sulfatase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

6 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016788 hydrolase activity, acting on ester bonds Catalysis of the hydrolysis of any ester bond.
GO:0008484 sulfuric ester hydrolase activity Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of a sulfuric ester bond, an ester formed from sulfuric acid, O=SO(OH)2.
GO:0004423 iduronate-2-sulfatase activity Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.

5 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0008484 GO:0004423
is_a GO:0016787 GO:0004423
is_a GO:0016788 GO:0004423
is_a GO:0003674 GO:0004423
is_a GO:0003824 GO:0004423

14 Synonyms

Name Type
iduronate sulfatase activity synonym
2-sulfo-L-iduronate 2-sulfatase activity synonym
iduronate-2-sulfate sulfatase activity synonym
iduronate sulfate sulfatase activity synonym
iduronide-2-sulfate sulfatase activity synonym
iduronate-2-sulphatase activity synonym
L-iduronate 2-sulfate sulfatase activity synonym
idurono-2-sulfatase activity synonym
L-idurono sulfate sulfatase activity synonym
L-iduronate-2-sulfate 2-sulfohydrolase activity synonym
sulfo-L-iduronate sulfatase activity synonym
L-iduronosulfatase activity synonym
sulfoiduronate sulfohydrolase activity synonym
chondroitinsulfatase synonym