WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0004467 long-chain fatty acid-CoA ligase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

10 Ontology Annotations

Annotation Extension Qualifier
  enables
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28 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0032787 monocarboxylic acid metabolic process The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).
GO:0019752 carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
GO:0006629 lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
GO:0043436 oxoacid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
GO:0006082 organic acid metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
GO:0044281 small molecule metabolic process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
GO:0006631 fatty acid metabolic process The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
GO:0016874 ligase activity Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient.
GO:0016877 ligase activity, forming carbon-sulfur bonds Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.
GO:0017111 ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
GO:0016887 ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0140657 ATP-dependent activity A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0001676 long-chain fatty acid metabolic process The chemical reactions and pathways involving a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
GO:0016405 CoA-ligase activity Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA.
GO:0016878 acid-thiol ligase activity Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GO:0120515 fatty acid-CoA ligase activity Catalysis of the reaction: a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate.
GO:0004467 long-chain fatty acid-CoA ligase activity Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
GO:0015645 fatty acid ligase activity Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.

33 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0120515 GO:0004467
part of GO:0001676 GO:0004467
part of GO:0006629 GO:0004467
is_a GO:0016874 GO:0004467
has part GO:0016817 GO:0004467
has part GO:0016818 GO:0004467
part of GO:0044281 GO:0004467
part of GO:0044238 GO:0004467
part of GO:0008150 GO:0004467
part of GO:0008152 GO:0004467
is_a GO:0003674 GO:0004467
is_a GO:0015645 GO:0004467
has part GO:0003824 GO:0004467
is_a GO:0016877 GO:0004467
is_a GO:0016878 GO:0004467
part of GO:0006631 GO:0004467
is_a GO:0140657 GO:0004467
part of GO:0009987 GO:0004467
has part GO:0016787 GO:0004467
has part GO:0016887 GO:0004467
has part GO:0016462 GO:0004467
has part GO:0017111 GO:0004467
is_a GO:0003824 GO:0004467
part of GO:0032787 GO:0004467
has part GO:0003674 GO:0004467
part of GO:0019752 GO:0004467
part of GO:0006082 GO:0004467
is_a GO:0016405 GO:0004467
part of GO:0043436 GO:0004467
is_a GO:0004467 GO:0047676

18 Synonyms

Name Type
GO:0003996 alt_id
acyl-activating enzyme activity synonym
acyl-CoA ligase activity synonym
acyl-CoA synthetase activity synonym
fatty acid thiokinase (long-chain) activity synonym
LCFA synthetase activity synonym
lignoceroyl-CoA synthase activity synonym
long chain fatty acyl-CoA synthetase activity synonym
long-chain acyl CoA synthetase activity synonym
long-chain acyl-CoA synthetase activity synonym
long-chain acyl-coenzyme A synthetase activity synonym
long-chain fatty acid activation synonym
long-chain fatty acyl coenzyme A synthetase activity synonym
long-chain-fatty-acid-CoA ligase activity synonym
long-chain-fatty-acyl-CoA synthetase activity synonym
pristanoyl-CoA synthetase synonym
stearoyl-CoA synthetase synonym
thiokinase synonym