GO:0003674
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molecular_function
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A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
GO:0016740
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transferase activity
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Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
GO:0016765
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transferase activity, transferring alkyl or aryl (other than methyl) groups
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Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor). |
GO:0004659
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prenyltransferase activity
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Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor). |
GO:0140096
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catalytic activity, acting on a protein
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Catalytic activity that acts to modify a protein. |
GO:0008318
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protein prenyltransferase activity
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Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein. |
GO:0004661
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protein geranylgeranyltransferase activity
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Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein. |
GO:0004662
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CAAX-protein geranylgeranyltransferase activity
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Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families. |