WormMine: GOTerm GO:0004725 protein tyrosine phosphatase activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

891 Ontology Annotations

9 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787	hydrolase activity	Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016788	hydrolase activity, acting on ester bonds	Catalysis of the hydrolysis of any ester bond.
GO:0140096	catalytic activity, acting on a protein	Catalytic activity that acts to modify a protein.
GO:0016791	phosphatase activity	Catalysis of the hydrolysis of a phosphoric monoester, releasing a phosphate.
GO:0042578	phosphoric ester hydrolase activity	Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
GO:0004721	phosphoprotein phosphatase activity	Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cellular proteins and thereby provide an important mechanism for regulating cellular activity.
GO:0004725	protein tyrosine phosphatase activity	Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

13 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0004721	GO:0004725
is_a	GO:0003824	GO:0004725
is_a	GO:0140096	GO:0004725
is_a	GO:0016791	GO:0004725
is_a	GO:0042578	GO:0004725
is_a	GO:0003674	GO:0004725
is_a	GO:0016787	GO:0004725
is_a	GO:0016788	GO:0004725
is_a	GO:0004725	GO:0004726
is_a	GO:0004725	GO:0005001
positively regulates	GO:0004725	GO:0008160
is_a	GO:0004725	GO:0030946
is_a	GO:0004725	GO:0033550

14 Synonyms

• Name: phosphotyrosine protein phosphatase activity
• Type: synonym

• Name: phosphotyrosine phosphatase activity
• Type: synonym

• Name: PPT-phosphatase activity
• Type: synonym

• Name: phosphotyrosylprotein phosphatase activity
• Type: synonym

• Name: protein-tyrosine-phosphatase activity
• Type: synonym

• Name: protein phosphotyrosine phosphatase activity
• Type: synonym

• Name: PTP-phosphatase activity
• Type: synonym

• Name: protein-tyrosine-phosphate phosphohydrolase activity
• Type: synonym

• Name: tyrosine O-phosphate phosphatase activity
• Type: synonym

• Name: PTPase activity
• Type: synonym

• Name: tyrosylprotein phosphatase activity
• Type: synonym

• Name: [phosphotyrosine]protein phosphatase activity
• Type: synonym

• Name: phosphotyrosine histone phosphatase activity
• Type: synonym

• Name: phosphoprotein phosphatase (phosphotyrosine) activity
• Type: synonym