WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

28 Ontology Annotations

Annotation Extension Qualifier
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7 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.
GO:0004738 pyruvate dehydrogenase activity Catalysis of the oxidative decarboxylation of pyruvate.
GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2.

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016624 GO:0004739
is_a GO:0004738 GO:0004739
is_a GO:0016903 GO:0004739
is_a GO:0016491 GO:0004739
is_a GO:0003824 GO:0004739
is_a GO:0003674 GO:0004739
has part GO:0004739 GO:0034604

6 Synonyms

Name Type
pyruvate dehydrogenase (lipoamide) activity synonym
pyruvate dehydrogenase complex activity synonym
pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating) synonym
pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity synonym
MtPDC (mitochondrial pyruvate dehydogenase complex) activity synonym
PDH synonym