WormMine: GOTerm GO:0004767 sphingomyelin phosphodiesterase activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

47 Ontology Annotations

9 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787	hydrolase activity	Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016788	hydrolase activity, acting on ester bonds	Catalysis of the hydrolysis of any ester bond.
GO:0042578	phosphoric ester hydrolase activity	Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
GO:0008081	phosphoric diester hydrolase activity	Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
GO:0016298	lipase activity	Catalysis of the hydrolysis of a lipid.
GO:0004620	phospholipase activity	Catalysis of the hydrolysis of a glycerophospholipid.
GO:0004767	sphingomyelin phosphodiesterase activity	Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+.

11 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0004620	GO:0004767
is_a	GO:0008081	GO:0004767
is_a	GO:0016298	GO:0004767
is_a	GO:0016788	GO:0004767
is_a	GO:0042578	GO:0004767
is_a	GO:0003674	GO:0004767
is_a	GO:0016787	GO:0004767
is_a	GO:0003824	GO:0004767
positively regulates	GO:0004767	GO:0016230
is_a	GO:0004767	GO:0061750
is_a	GO:0004767	GO:0061751

4 Synonyms

• Name: sphingomyelin cholinephosphohydrolase activity
• Type: synonym

• Name: sphingomyelinase activity
• Type: synonym

• Name: GO:0030230
• Type: alt_id

• Name: GO:0030231
• Type: alt_id