WormMine: GOTerm GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

79 Ontology Annotations

21 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740	transferase activity	Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0005488	binding	The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0140096	catalytic activity, acting on a protein	Catalytic activity that acts to modify a protein.
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
GO:0016301	kinase activity	Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0004674	protein serine/threonine kinase activity	Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
GO:0004672	protein kinase activity	Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
GO:0016773	phosphotransferase activity, alcohol group as acceptor	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).
GO:0016772	transferase activity, transferring phosphorus-containing groups	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0097472	cyclin-dependent protein kinase activity	Cyclin-dependent catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
GO:0005515	protein binding	Binding to a protein.
GO:0098772	molecular function regulator activity	A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0019899	enzyme binding	Binding to an enzyme, a protein with catalytic activity.
GO:0030234	enzyme regulator activity	Binds to and modulates the activity of an enzyme.
GO:0019887	protein kinase regulator activity	Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.
GO:0019207	kinase regulator activity	Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0019901	protein kinase binding	Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
GO:0019900	kinase binding	Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group.
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.

24 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0016538	GO:0004861
regulates	GO:0004693	GO:0016538
is_a	GO:0019887	GO:0016538
regulates	GO:0004672	GO:0016538
regulates	GO:0097472	GO:0016538
is_a	GO:0030234	GO:0016538
regulates	GO:0004674	GO:0016538
regulates	GO:0003674	GO:0016538
is_a	GO:0019207	GO:0016538
has part	GO:0005515	GO:0016538
has part	GO:0003674	GO:0016538
has part	GO:0005488	GO:0016538
regulates	GO:0016773	GO:0016538
regulates	GO:0016740	GO:0016538
regulates	GO:0016772	GO:0016538
regulates	GO:0016301	GO:0016538
regulates	GO:0140096	GO:0016538
is_a	GO:0003674	GO:0016538
has part	GO:0019899	GO:0016538
regulates	GO:0003824	GO:0016538
has part	GO:0019901	GO:0016538
has part	GO:0019900	GO:0016538
is_a	GO:0098772	GO:0016538
is_a	GO:0016538	GO:0061575

8 Synonyms

• Name: GO:0003752
• Type: alt_id

• Name: GO:0003753
• Type: alt_id

• Name: G2/M-specific cyclin
• Type: synonym

• Name: GO:0003751
• Type: alt_id

• Name: cyclin-dependent protein kinase, intrinsic regulator activity
• Type: synonym

• Name: G1/S-specific cyclin
• Type: synonym

• Name: cyclin
• Type: synonym

• Name: cyclin-dependent protein kinase regulator activity
• Type: synonym