WormMine: GOTerm GO:0004864 protein phosphatase inhibitor activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: Binds to and stops, prevents or reduces the activity of a protein phosphatase.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

18 Ontology Annotations

21 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787	hydrolase activity	Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016788	hydrolase activity, acting on ester bonds	Catalysis of the hydrolysis of any ester bond.
GO:0005488	binding	The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0140096	catalytic activity, acting on a protein	Catalytic activity that acts to modify a protein.
GO:0016791	phosphatase activity	Catalysis of the hydrolysis of a phosphoric monoester, releasing a phosphate.
GO:0042578	phosphoric ester hydrolase activity	Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
GO:0005515	protein binding	Binding to a protein.
GO:0098772	molecular function regulator activity	A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0019899	enzyme binding	Binding to an enzyme, a protein with catalytic activity.
GO:0019212	phosphatase inhibitor activity	Binds to and stops, prevents or reduces the activity of a phosphatase.
GO:0019902	phosphatase binding	Binding to a phosphatase.
GO:0019208	phosphatase regulator activity	Binds to and modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
GO:0030234	enzyme regulator activity	Binds to and modulates the activity of an enzyme.
GO:0004857	enzyme inhibitor activity	Binds to and stops, prevents or reduces the activity of an enzyme.
GO:0140678	molecular function inhibitor activity	A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0004721	phosphoprotein phosphatase activity	Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cellular proteins and thereby provide an important mechanism for regulating cellular activity.
GO:0004864	protein phosphatase inhibitor activity	Binds to and stops, prevents or reduces the activity of a protein phosphatase.
GO:0019888	protein phosphatase regulator activity	Binds to and modulates the activity of a protein phosphatase.
GO:0019903	protein phosphatase binding	Binding to a protein phosphatase.

31 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0019212	GO:0004864
is_a	GO:0019888	GO:0004864
negatively regulates	GO:0004721	GO:0004864
negatively regulates	GO:0016788	GO:0004864
negatively regulates	GO:0016787	GO:0004864
negatively regulates	GO:0042578	GO:0004864
has part	GO:0019903	GO:0004864
regulates	GO:0140096	GO:0004864
regulates	GO:0016791	GO:0004864
negatively regulates	GO:0003824	GO:0004864
has part	GO:0019902	GO:0004864
regulates	GO:0003674	GO:0004864
has part	GO:0005488	GO:0004864
is_a	GO:0003674	GO:0004864
regulates	GO:0004721	GO:0004864
is_a	GO:0019208	GO:0004864
is_a	GO:0140678	GO:0004864
regulates	GO:0042578	GO:0004864
has part	GO:0019899	GO:0004864
regulates	GO:0016787	GO:0004864
regulates	GO:0016788	GO:0004864
negatively regulates	GO:0140096	GO:0004864
regulates	GO:0003824	GO:0004864
negatively regulates	GO:0016791	GO:0004864
is_a	GO:0098772	GO:0004864
is_a	GO:0004857	GO:0004864
has part	GO:0003674	GO:0004864
negatively regulates	GO:0003674	GO:0004864
is_a	GO:0030234	GO:0004864
has part	GO:0005515	GO:0004864

4 Synonyms

• Name: protein phosphatase 2 inhibitor activity
• Type: synonym

• Name: protein phosphatase type 2A inhibitor activity
• Type: synonym

• Name: phosphoprotein phosphatase inhibitor activity
• Type: synonym

• Name: GO:1990681
• Type: alt_id