WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:1990806 ligand-gated ion channel signaling pathway GO

Namespace  biological_process Obsolete  false
Description  The series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

1 Ontology Annotations

Annotation Extension Qualifier
  involved_in

21 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0022857 transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0015075 monoatomic ion transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0023052 signaling The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0007154 cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0015267 channel activity Enables the energy-independent facilitated diffusion of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
GO:0022803 passive transmembrane transporter activity Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.
GO:0015276 ligand-gated monoatomic ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
GO:0005216 monoatomic ion channel activity Enables the facilitated diffusion of a monoatomic ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
GO:0022836 gated channel activity Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.
GO:0022834 ligand-gated channel activity Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
GO:1990806 ligand-gated ion channel signaling pathway The series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription.

41 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:1990806 GO:0004970
part of GO:1990806 GO:0004971
part of GO:1990806 GO:0004972
part of GO:1990806 GO:0015277
part of GO:1990806 GO:0022849
is_a GO:1990806 GO:0035235
is_a GO:1990806 GO:0098989
is_a GO:1990806 GO:0098990
is_a GO:1990806 GO:0098991
regulates GO:1990806 GO:0106426
regulates GO:1990806 GO:0106427
regulates GO:1990806 GO:0106428
is_a GO:1990806 GO:0140227
has part GO:0015276 GO:1990806
is_a GO:0007165 GO:1990806
has part GO:0015276 GO:1990806
is_a GO:0007165 GO:1990806
part of GO:0008150 GO:1990806
part of GO:0065007 GO:1990806
is_a GO:0009987 GO:1990806
regulates GO:0009987 GO:1990806
is_a GO:0065007 GO:1990806
part of GO:0009987 GO:1990806
has part GO:0022803 GO:1990806
has part GO:0015075 GO:1990806
has part GO:0015267 GO:1990806
is_a GO:0008150 GO:1990806
is_a GO:0050789 GO:1990806
regulates GO:0008150 GO:1990806
part of GO:0007154 GO:1990806

1 Synonyms

Name Type
ligand-gated ion channel signalling pathway synonym