WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0005095 GTPase inhibitor activity GO

Namespace  molecular_function Obsolete  false
Description  Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

1 Ontology Annotations

Annotation Extension Qualifier
has_input(WB:WBGene00002335) enables

17 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.
GO:0017111 ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0004857 enzyme inhibitor activity Binds to and stops, prevents or reduces the activity of an enzyme.
GO:0140678 molecular function inhibitor activity A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0003924 GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
GO:0030695 GTPase regulator activity Binds to and modulates the activity of a GTPase.
GO:0060589 nucleoside-triphosphatase regulator activity Binds to and modulates the activity of an NTPase.
GO:0005095 GTPase inhibitor activity Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.

26 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
negatively regulates GO:0003924 GO:0005095
is_a GO:0004857 GO:0005095
is_a GO:0030695 GO:0005095
negatively regulates GO:0016817 GO:0005095
is_a GO:0060589 GO:0005095
regulates GO:0016817 GO:0005095
regulates GO:0016818 GO:0005095
regulates GO:0003674 GO:0005095
negatively regulates GO:0016818 GO:0005095
negatively regulates GO:0016787 GO:0005095
has part GO:0005515 GO:0005095
is_a GO:0140678 GO:0005095
regulates GO:0016787 GO:0005095
has part GO:0005488 GO:0005095
is_a GO:0030234 GO:0005095
has part GO:0003674 GO:0005095
regulates GO:0016462 GO:0005095
regulates GO:0017111 GO:0005095
negatively regulates GO:0003824 GO:0005095
negatively regulates GO:0017111 GO:0005095
negatively regulates GO:0016462 GO:0005095
is_a GO:0003674 GO:0005095
is_a GO:0098772 GO:0005095
regulates GO:0003924 GO:0005095
regulates GO:0003824 GO:0005095
negatively regulates GO:0003674 GO:0005095

1 Synonyms

Name Type
GIP synonym