WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0005096 GTPase activator activity GO

Namespace  molecular_function Obsolete  false
Description  Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

340 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables
  enables
  enables
  enables
has_input(WB:WBGene00000424)|has_input(WB:WBGene00004357)|has_input(WB:WBGene00000390) enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  contributes_to
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables

17 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.
GO:0017111 ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0140677 molecular function activator activity A molecular function regulator that activates or increases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0003924 GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
GO:0030695 GTPase regulator activity Binds to and modulates the activity of a GTPase.
GO:0060589 nucleoside-triphosphatase regulator activity Binds to and modulates the activity of an NTPase.
GO:0005096 GTPase activator activity Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
GO:0008047 enzyme activator activity Binds to and increases the activity of an enzyme.

26 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0030695 GO:0005096
positively regulates GO:0003924 GO:0005096
is_a GO:0008047 GO:0005096
regulates GO:0016818 GO:0005096
positively regulates GO:0003824 GO:0005096
regulates GO:0016817 GO:0005096
has part GO:0003674 GO:0005096
is_a GO:0140677 GO:0005096
positively regulates GO:0003674 GO:0005096
regulates GO:0016787 GO:0005096
positively regulates GO:0016817 GO:0005096
positively regulates GO:0016818 GO:0005096
has part GO:0005488 GO:0005096
is_a GO:0030234 GO:0005096
regulates GO:0017111 GO:0005096
regulates GO:0016462 GO:0005096
regulates GO:0003924 GO:0005096
positively regulates GO:0016787 GO:0005096
has part GO:0005515 GO:0005096
is_a GO:0098772 GO:0005096
regulates GO:0003674 GO:0005096
regulates GO:0003824 GO:0005096
positively regulates GO:0017111 GO:0005096
is_a GO:0060589 GO:0005096
positively regulates GO:0016462 GO:0005096
is_a GO:0003674 GO:0005096

29 Synonyms

Name Type
Rho GAP activity synonym
Rho GTPase activator activity synonym
Sar GAP activity synonym
Sar GTPase activator activity synonym
GO:0005097 alt_id
GO:0005098 alt_id
GO:0005099 alt_id
GO:0005100 alt_id
GO:0005101 alt_id
GO:0008060 alt_id
GO:0017123 alt_id
GO:0030675 alt_id
GO:0046582 alt_id
ARF GAP activity synonym
ARF GTPase activator activity synonym
GAP activity synonym
Rab GAP activity synonym
Rab GTPase activator activity synonym
Rac GAP activity synonym
Rac GTPase activator activity synonym
Ral GAP activity synonym
Ral GTPase activator activity synonym
Ran GAP activity synonym
Ran GTPase activator activity synonym
RanGAP synonym
Rap GAP activity synonym
Rap GTPase activator activity synonym
Ras GAP activity synonym
Ras GTPase activator activity synonym