WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0005834 heterotrimeric G-protein complex GO

Namespace  cellular_component Obsolete  false
Description  Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

54 Ontology Annotations

Annotation Extension Qualifier
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17 Parents

Identifier Name Description
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:0071944 cell periphery The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.
GO:0098796 membrane protein complex Any protein complex that is part of a membrane.
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
GO:0005886 plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0098797 plasma membrane protein complex Any protein complex that is part of the plasma membrane.
GO:0019898 extrinsic component of membrane The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
GO:0005834 heterotrimeric G-protein complex Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein.
GO:1905360 GTPase complex A protein complex which is capable of GTPase activity.
GO:0009898 cytoplasmic side of plasma membrane The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
GO:0098562 cytoplasmic side of membrane The side of a membrane that faces the cytoplasm.
GO:0098552 side of membrane A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface.
GO:0019897 extrinsic component of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.

17 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0031234 GO:0005834
is_a GO:0098797 GO:0005834
is_a GO:1905360 GO:0005834
part of GO:0005575 GO:0005834
part of GO:0009898 GO:0005834
part of GO:0110165 GO:0005834
part of GO:0005886 GO:0005834
part of GO:0098562 GO:0005834
part of GO:0098552 GO:0005834
is_a GO:0098796 GO:0005834
part of GO:0019897 GO:0005834
part of GO:0019898 GO:0005834
part of GO:0016020 GO:0005834
is_a GO:0005575 GO:0005834
part of GO:0071944 GO:0005834
is_a GO:0032991 GO:0005834
is_a GO:1902494 GO:0005834

4 Synonyms

Name Type
heterotrimeric G-protein GTPase, beta-subunit synonym
heterotrimeric G-protein GTPase, gamma-subunit synonym
heterotrimeric G-protein GTPase activity synonym
heterotrimeric G-protein GTPase, alpha-subunit synonym