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GO:0009987
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cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0008150
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biological_process
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A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. |
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GO:0044238
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primary metabolic process
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The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
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GO:0090304
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nucleic acid metabolic process
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Any cellular metabolic process involving nucleic acids. |
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GO:0006139
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nucleobase-containing compound metabolic process
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Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. |
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GO:0008152
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metabolic process
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A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation. |
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GO:0043170
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macromolecule metabolic process
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The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
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GO:0009058
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biosynthetic process
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A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. |
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GO:0019538
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protein metabolic process
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The chemical reactions and pathways involving a protein. Includes protein modification. |
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GO:0009059
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macromolecule biosynthetic process
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The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
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GO:0006520
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amino acid metabolic process
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The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. |
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GO:0043412
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macromolecule modification
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The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. |
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GO:0016070
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RNA metabolic process
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The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. |
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GO:0010467
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gene expression
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The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes. |
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GO:0009451
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RNA modification
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The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. |
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GO:0006396
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RNA processing
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Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. |
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GO:0008033
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tRNA processing
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The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. |
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GO:0006399
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tRNA metabolic process
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The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. |
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GO:0006412
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translation
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The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
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GO:0019988
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charged-tRNA amino acid modification
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The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine. |
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GO:0001717
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conversion of seryl-tRNAsec to selenocys-tRNAsec
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The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine. |
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GO:0006400
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tRNA modification
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The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
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GO:0006418
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tRNA aminoacylation for protein translation
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The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis. |
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GO:0043039
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tRNA aminoacylation
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The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules. |
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GO:0043038
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amino acid activation
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The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. |
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GO:0006434
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seryl-tRNA aminoacylation
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The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA. |
