WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration GO

Namespace  biological_process Obsolete  false
Description  The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

14 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0007155 cell adhesion The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
GO:0048870 cell motility Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
GO:0016477 cell migration The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues.
GO:0030155 regulation of cell adhesion Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
GO:0007162 negative regulation of cell adhesion Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
GO:0006929 substrate-dependent cell migration The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate.
GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.

22 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0006929 GO:0006933
is_a GO:0007162 GO:0006933
part of GO:0006929 GO:0006933
is_a GO:0007162 GO:0006933
regulates GO:0008150 GO:0006933
part of GO:0009987 GO:0006933
part of GO:0048870 GO:0006933
is_a GO:0065007 GO:0006933
is_a GO:0048523 GO:0006933
part of GO:0016477 GO:0006933
is_a GO:0048519 GO:0006933
negatively regulates GO:0009987 GO:0006933
regulates GO:0009987 GO:0006933
part of GO:0008150 GO:0006933
negatively regulates GO:0007155 GO:0006933
is_a GO:0030155 GO:0006933
is_a GO:0050794 GO:0006933
regulates GO:0007155 GO:0006933
negatively regulates GO:0008150 GO:0006933
is_a GO:0050789 GO:0006933
is_a GO:0008150 GO:0006933
part of GO:0006933 GO:0006934

1 Synonyms

Name Type
substrate-bound cell migration, cell release from substrate synonym