WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0051350 negative regulation of lyase activity GO

Namespace  biological_process Obsolete  false
Description  Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

10 Parents

Identifier Name Description
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0016829 lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
GO:0044092 negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0043086 negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
GO:0051350 negative regulation of lyase activity Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.

24 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has part GO:0051350 GO:0007193
is_a GO:0051350 GO:0007194
has part GO:0051350 GO:0007195
has part GO:0051350 GO:0007196
has part GO:0051350 GO:0007197
has part GO:0051350 GO:0007198
is_a GO:0051350 GO:0031283
has part GO:0051350 GO:0031635
is_a GO:0065007 GO:0051350
is_a GO:0043086 GO:0051350
negatively regulates GO:0016829 GO:0051350
negatively regulates GO:0016829 GO:0051350
is_a GO:0008150 GO:0051350
regulates GO:0003824 GO:0051350
is_a GO:0065007 GO:0051350
negatively regulates GO:0003824 GO:0051350
is_a GO:0050790 GO:0051350
regulates GO:0003674 GO:0051350
negatively regulates GO:0003674 GO:0051350
is_a GO:0065009 GO:0051350
is_a GO:0044092 GO:0051350
has part GO:0051350 GO:0071881
is_a GO:0051350 GO:1904042
is_a GO:0051350 GO:1904233

5 Synonyms

Name Type
down regulation of lyase activity synonym
down-regulation of lyase activity synonym
downregulation of lyase activity synonym
inhibition of lyase activity synonym
lyase inhibitor synonym