WormMine: Gene WBGene00202503

• WormBase Gene ID: WBGene00202503
• Gene Name: let-75
• Organism: Caenorhabditis elegans
• Automated Description: Is affected by several genes including mut-16; pry-1; and hpl-2 based on microarray; RNA-seq; and proteomic studies.
• Genetic Position: :±

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

0 Synonyms

Genomics

0 Transcripts

Other

0 CDSs

0 RNAi Result

4 Allele

• s101
• s107
• s108
• s143

0 Chromosome

0 Chromosome Location

1 Data Sets

• WormBaseAcedbConverter

0 Downstream Intergenic Region

18 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
adult vs dauer larva	Transcripts that showed differential expression in adult vs dauer lava in N2 animals at 20C.	N.A.	WBPaper00050488:adult_vs_dauer_regulated_N2_20C
	Transcripts that showed differential expression in dauer mir-34(gk437) vs dauer mir-34(OverExpression) animals at 20C.	N.A.	WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
	Transcripts that showed differential expression in dauer N2 vs dauer mir-34(gk437) animals at 20C.	N.A.	WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
	Transcripts that showed significantly decreased expression in pry-1(mu38) animals comparing to in N2 at L1 larva stage.	DESeq, FDR < 0.05	WBPaper00055626:pry-1(mu38)_downregulated
	Proteins expressed in intestine cytoplasm, according to tissue specific APX enzyme expression using spp-5 promoter driven NES(cytoplasm)-GFP-APX, followed with mass spectrometry.	Fold change > 2.	WBPaper00051245:intestine_cytoplasm_expressed
	Transcripts that showed significantly increased expression in hpl-2(tm1489) comparing to in N2 animals.	DESeq2, adjusted p-value < 0.05, log2 fold change > 2 or < -2.	WBPaper00054493:hpl-2(tm1489)_upregulated
	Proteins specifically expressed in cytoplasm, according to tissue specific APX enzyme expression driven NES(cytoplasm)-GFP-APX, followed with mass spectrometry.	Fold change > 2.	WBPaper00051245:cytoplasm_specific
	Proteins expressed in epidermis cytoplasm, according to tissue specific APX enzyme expression using dpy-7 promoter driven NES(cytoplasm)-GFP-APX, followed with mass spectrometry.	Fold change > 2.	WBPaper00051245:epidermis_cytoplasm_expressed
	Proteins expressed in epidermis nucleus, according to tissue specific APX enzyme expression using dpy-7 promoter driven NLS(nucleus)-GFP-APX, followed with mass spectrometry.	Fold change > 2.	WBPaper00051245:epidermis_nucleus_expressed
	Proteins expressed in pharyngeal muscle cytoplasm, according to tissue specific APX enzyme expression using myo-2 promoter driven NES(cytoplasm)-GFP-APX, followed with mass spectrometry.	Fold change > 2.	WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
	Transcripts that were depleted in embryonic primordial germ cells (PGCs) comparing to in whole embryo, according to NuGen RNAseq.	For differential gene expression analysis, sets of independent mutant and control mapped reads (e.g biological replicates) were used in cuffdiff analysis. The cutoff of FDR(q value)=0.05 was used as a significance cutoff for all the analyses.	WBPaper00053321:PGCs_depleted_NuGen
	Transcripts that showed differential expression in dauer daf-2(e1370) vs dauer daf-2(e1370);mir-34(gk437) animals at 25C.	N.A.	WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
	Transcripts that showed differential expression in adult mir-34(gk437) vs adult mir-34(OverExpression) animals at 20C.	N.A.	WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
	Proteins that physically interact with MUT-16 according to MUT-16-GFP-3xFLAG immunoprecipitation.	N.A.	WBPaper00059605:MUT-16_interacting
	Secreted proteins that bind E. coli pellet.	N.A.	WBPaper00064933:E.coli-binding_secret_protein
	Transcripts that showed significantly increased expression in starved nos-1(gv5)nos-2(RNAi);lin-15B(RNAi) comparing to in starved nos-1(gv5)nos-2(RNAi), in primordial germ cells (PGCs) at L1 larva, according to Truseq.	For differential gene expression analysis, sets of independent mutant and control mapped reads (e.g biological replicates) were used in cuffdiff analysis. The cutoff of FDR(q value)=0.05 was used as a significance cutoff for all the analyses.	WBPaper00053321:lin-15B(RNAi)_upregulated_starved-L1_Truseq
	Proteins expressed in pharyngeal muscle nucleus, according to tissue specific APX enzyme expression using myo-2 promoter driven NLS(nucleus)-GFP-APX, followed with mass spectrometry.	Fold change > 2.	WBPaper00051245:pharyngeal-muscle_nucleus_expressed
	Proteins that interact with polyadenylated mRNAs, according to proteomics analysis.	FDR < 5%	WBPaper00048910:mRNA-interacting_protein

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term