WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0007597 blood coagulation, intrinsic pathway GO

Namespace  biological_process Obsolete  false
Description  A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

24 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0009058 biosynthetic process A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a protein. Includes protein modification.
GO:0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010467 gene expression The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes.
GO:0065008 regulation of biological quality Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
GO:0032501 multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0042060 wound healing The series of events that restore integrity to a damaged tissue, following an injury.
GO:0009611 response to wounding Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
GO:0051604 protein maturation Any process leading to the attainment of the full functional capacity of a protein.
GO:0072376 protein activation cascade A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events.
GO:0050878 regulation of body fluid levels Any process that modulates the levels of body fluids.
GO:0050817 coagulation The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.
GO:0007596 blood coagulation The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
GO:0007599 hemostasis The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.
GO:0007597 blood coagulation, intrinsic pathway A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.
GO:0072378 blood coagulation, fibrin clot formation A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.

39 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0072376 GO:0007597
part of GO:0072378 GO:0007597
part of GO:0072376 GO:0007597
is_a GO:0008152 GO:0007597
is_a GO:0008150 GO:0007597
part of GO:0010467 GO:0007597
part of GO:0008150 GO:0007597
part of GO:0043170 GO:0007597
part of GO:0042060 GO:0007597
part of GO:0008152 GO:0007597
is_a GO:0051604 GO:0007597
is_a GO:0043170 GO:0007597
part of GO:0006950 GO:0007597
part of GO:0009987 GO:0007597
part of GO:0044238 GO:0007597
part of GO:0050896 GO:0007597
is_a GO:0019538 GO:0007597
part of GO:0032501 GO:0007597
part of GO:0050817 GO:0007597
part of GO:0050878 GO:0007597
part of GO:0051604 GO:0007597
part of GO:0019538 GO:0007597
part of GO:0065008 GO:0007597
part of GO:0007596 GO:0007597
part of GO:0009059 GO:0007597
part of GO:0065007 GO:0007597
part of GO:0009058 GO:0007597
is_a GO:0009987 GO:0007597
is_a GO:0044238 GO:0007597
part of GO:0007599 GO:0007597

0 Synonyms