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GO:0032991
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protein-containing complex
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A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
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GO:0005575
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cellular_component
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A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
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GO:0110165
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cellular anatomical structure
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A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. |
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GO:0071944
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cell periphery
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The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. |
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GO:0098796
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membrane protein complex
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Any protein complex that is part of a membrane. |
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GO:0016020
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membrane
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A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. |
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GO:1990351
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transporter complex
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A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. |
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GO:1902495
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transmembrane transporter complex
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A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other. |
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GO:0005886
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plasma membrane
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The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
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GO:0098797
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plasma membrane protein complex
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Any protein complex that is part of the plasma membrane. |
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GO:0034703
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cation channel complex
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An ion channel complex through which cations pass. |
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GO:0034702
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monoatomic ion channel complex
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A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective monoatomic ion transport down its electrochemical gradient. |
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GO:0034705
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potassium channel complex
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An ion channel complex through which potassium ions pass. |
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GO:0008282
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inward rectifying potassium channel
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A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity. |
