WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

Allele :

Public Name  s1710 KO Consortium Allele  false
NBP Allele  false Nema GENETAG Consortium Allele  false
Other Name  CE42707:p.Asp309ValfsTer20 WormBase ID  WBVar00242191
Sequence Status  Sequenced Species  Caenorhabditis elegans
Status  Live Type  Allele
Type Of Mutation  Deletion

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006763 unc-26 JC8.10 Caenorhabditis elegans

0 Gene Class

20 Phenotype

Identifier Name Description
WBPhenotype:0000643 locomotion variant Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals.
WBPhenotype:0001345 cytoskeleton organization biogenesis variant Animals exhibit variations in the form, structure, composition or arrangement of any of the various filamentous elements that form the internal framework of cells, compared to control. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
WBPhenotype:0000644 paralyzed Animals do not move and are not responsive to external mechanical stimulation.
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0000672 presynaptic vesicle cluster localization variant Animals display variations in the distribution of transmitter-filled vesicles in relation to the electron-dense membrane specialization of the neuron,compared to that observed in control animals.
WBPhenotype:0000017 aldicarb resistant Animals fail to respond to the concentration of aldicarb that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0000654 synaptic vesicle exocytosis variant Animals exhibit variations in the fusion of intracellular neurotransmitter-filled membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell compared to control.
WBPhenotype:0001671 vesicle organization variant Animals display variations in the distribution of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals.
WBPhenotype:0002371 vesicle maturation defective Vesicles, including those in cells, cell bodies, or synaptic terminals, do not properly form or maintain an intermediate state, such as remain coated with a clathrin coat.
WBPhenotype:0002372 presynaptic vesicle morphology altered Vesicles in the presynaptic terminal differ in size, shape, or composition from those observed in control animals.
WBPhenotype:0002473 autophagy block Animals fail to undergo the cellular catabolic process in which cells digest parts of their own cytoplasm.
WBPhenotype:0000210 defecation contraction variant Any variation in the stereotyped muscle contractions that result in defecation compared to control . In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp).
WBPhenotype:0001803 endosome biogenesis variant Animals exhibit variations in the formation or disassembly of membrane bound organelles that traffic material between the plasma membrane and internal compartments of the cell, compared to control.
WBPhenotype:0001864 protein transport variant Any variation in the processes that modulate the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore compared to control.
WBPhenotype:0000612 nervous system physiology variant Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the nervous system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals.
WBPhenotype:0001316 evoked postsynaptic current variant Variations in the synaptic currents that are elicited by firing an action potential in a population of axons, compared to control.
WBPhenotype:0001321 presynaptic region morphology variant Animals display variations in the structure, configuration, distribution or ratio of the components of the vesicle-filled varicosities of the synapse compared to control.
WBPhenotype:0001670 presynaptic vesicle number reduced Animals exhibit an overall decrease in the quantity of synaptic vesicles at the synapse compared to control animals.
WBPhenotype:0000153 body wall muscle contraction abnormal Initiation, strength, extent or cessation of body wall muscle activity that results in the shortening of the muscle, is aberrant compared to control animals.
WBPhenotype:0001514 synaptic vesicle endocytosis variant Variations in the uptake of a small membrane-bound organelle, filled with neurotransmitter(s) and/or neuropeptides, by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle compared to control(Wormatlas).

5 Phenotype Not Observed

Identifier Name Description
WBPhenotype:0000306 transgene expression variant Any variation in the characteristic expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to control animals.
WBPhenotype:0000072 body morphology variant Animals exhibit variations in the form, structure or composition of any portion of their anatomy between the head and the tail compared to control animals.
WBPhenotype:0000673 brood size variant The number of offspring produced is altered compared to that of control animals.
WBPhenotype:0000676 growth rate variant The increase in size or mass of an organism over time during the lifespan of the organism or over any developmental stage(s) is not similar to that observed for control animals.
WBPhenotype:0000623 nervous system development variant Any variation in the progression of nervous tissue over time, from its formation to its mature state compared to control.

1 Strains

WormBase ID
WBStrain00006678