WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Phenotype : WBPhenotype:0000743 RNAi response variant

Description  Animals exhibit variations in their response to gene silencing triggered by double stranded RNA (RNAi), compared to control.

5 RNAi

WormBase ID
WBRNAi00022790
WBRNAi00097094
WBRNAi00022791
WBRNAi00062925
WBRNAi00062926

0 RNAi Not Observed

11 Children

Identifier Name Description
WBPhenotype:0001769 cytoplasmic RNAi defective Animals fail to silence cytoplasmic-localized RNAs. Nuclear-localized RNAs may still be sensitive to RNAi.
WBPhenotype:0000029 systemic RNAi variant Animals are defective for RNAi introduced by environmental means such as in the cases of RNAi triggered by soaking or feeding.
WBPhenotype:0001208 RNAi resistant Animals show reduced susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control.
WBPhenotype:0001828 RNAi persistence variant Variations in the persistence of an RNAi induced phenotype compared to control.
WBPhenotype:0001258 RNAi enhanced Animals show increased susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control.
WBPhenotype:0002374 RNAi transport defective Animals are deficient in the transport of silencing RNAs between cells during the systemic RNAi response process.
WBPhenotype:0001771 endo siRNA production variant Animals exhibit variations in the length or amount of any endogenous small interfering RNA molecule populations compared to control.
WBPhenotype:0001778 nuclear RNAi defective Animals fail to silence nuclear-localized RNAs. Animals still retain sensitivity to RNAi for those RNAs located outside of the nucleus.
WBPhenotype:0002145 siRNA processing defective Animals are unable to produce or maintain short interfering RNA (siRNA) from double stranded RNA (dsRNA). siRNAs are required to initiate interference of gene expression.
WBPhenotype:0002150 exo-RNAi response variant RNAi silencing mechanisms triggered by exogenously introduced (foreign) dsRNA, do not work to the same degree as in control animals.
WBPhenotype:0001770 endo siRNA binding variant Animals exhibit variations in their selective interactions with small interfering RNA molecules compared to control.

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Parents

Identifier Name Description
WBPhenotype:0000577 organism homeostasis metabolism variant Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the organism compared to control.

15 Phenotype Allele

Public Name
sa73
sy605
tm902
n488
e2917
md1971
bn11
pk1417
ok589
ne299
ne300
ok952
tm1637
y9
ok1417

35 Phenotype Allele Not Observed

Public Name
ma161
sy326
tm633
tm557
tm502
tm770
tm753
tm830
tm843
tm872
tm968
jw1
tm1050
ma104
tm3388
ne299
ne300
n4358
pk2298
n4357
n4503
tm996
ok1761
tm1340
tm3383
tm3121
tm1452
tm1569
tm1575
tm1803

2 Synonyms

Name Type
Rde  
RNAi response abnormal