WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

Allele :

Public Name  sa307 KO Consortium Allele  false
NBP Allele  false Nema GENETAG Consortium Allele  false
Other Name  F22E12.4c.1:c.199_309+2del WormBase ID  WBVar00242554
Sequence Status  Sequenced Species  Caenorhabditis elegans
Status  Live Type  Allele
Type Of Mutation  Deletion

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001178 egl-9 F22E12.4 Caenorhabditis elegans

0 Gene Class

21 Phenotype

Identifier Name Description
WBPhenotype:0001014 pathogen resistance increased Animals are less prone to infection compared to control.
WBPhenotype:0001276 ectopic expression transgene Any variation in the cellular expression of a gene product produced by exogenous DNA that has been introduced into the organism such that it now expresses in cells/tissues not seen when compared to the expression of that gene product in control animals.
WBPhenotype:0000136 mRNA levels increased Animals exhibit elevated levels of messenger RNA compared to control.
WBPhenotype:0000640 egg laying variant Animals exhibit variations in the stage of eggs laid, egg laying cycle, number of eggs or egg laying in response to stimuli compared to control.
WBPhenotype:0000061 extended life span The duration of viability in the adult phase of the life-cycle surpasses that of control animals.
WBPhenotype:0001236 transgene expression increased Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001013 pathogen susceptibility increased Animals are more prone to infection compared to control.
WBPhenotype:0001663 organism oxidative stress resistant Animals fail to respond to the levels of reactive oxygen species that elicit a response in control animals.
WBPhenotype:0000436 protein subcellular localization variant Any variation in the placement of a protein within in a cell or cellular compartment compared to control.
WBPhenotype:0001645 protein degradation variant Variations in the chemical reactions and pathways resulting in the directed breakdown of a protein (via the destruction of its native, active configuration) compared to control.
WBPhenotype:0000384 axon guidance variant Variations in the cue-directed extension of an axon towards a specific target site compared to control. (Axon guidance often depends on a combination of attractive and repulsive cues).
WBPhenotype:0000135 gene expression level high Animals exhibit an increase in the intensity of expression of a gene product compared to that observed in control animals.
WBPhenotype:0002378 pathogen avoidance variant Variations in the characteristic movement away from specific disease causing agents (pathogens) compared to control animals.
WBPhenotype:0001462 sodium chloride chemotaxis variant Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium chloride. In C. elegans, at specific concentrations, sodium chloride is an attractant.
WBPhenotype:0002060 pore forming toxin resistant Animals fail to respond to the concentration of pore forming toxins that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0001719 unfolded protein response variant Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.
WBPhenotype:0000067 organism stress response variant Animals exhibit variations in response to stress stimuli compared to control animals.
WBPhenotype:0000295 thermotolerance increased Animals are able to survive for longer periods at temperatures above standard culture temperatures than control animals.
WBPhenotype:0002652 exopher production increased Cells exhibit a increase in production of exophers compared to controls.
WBPhenotype:0001765 carbon dioxide avoidance variant Variations in the characteristic movement away from specific CO2 levels compared to control. C. elegans avoids high levels of CO2.
WBPhenotype:0001400 level of protein expression variant Animals exhibit variations in the measured expression of a protein compared to that observed in control animals.

2 Phenotype Not Observed

Identifier Name Description
WBPhenotype:0001381 anoxia resistant Animals fail to respond to trace amounts of oxygen that elicit a response in control animals.
WBPhenotype:0001990 hypoxia resistant Animals fail to respond to low amounts of oxygen that elicit a response in control animals.

5 Strains

WormBase ID
WBStrain00022795
WBStrain00040834
WBStrain00040846
WBStrain00004678
WBStrain00004676