WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

8 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.
GO:0004497 monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
GO:0008395 steroid hydroxylase activity Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.
GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor.
GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O.

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0008395 GO:0008386
is_a GO:0016713 GO:0008386
is_a GO:0016491 GO:0008386
is_a GO:0016705 GO:0008386
is_a GO:0003824 GO:0008386
is_a GO:0003674 GO:0008386
is_a GO:0004497 GO:0008386

17 Synonyms

Name Type
cholesterol 20-22-desmolase activity synonym
C27-side chain cleavage enzyme synonym
cholesterol C20-22 desmolase activity synonym
cholesterol C(20-22) desmolase activity synonym
cholesterol side-chain cleavage enzyme activity synonym
cholesterol desmolase activity synonym
cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving) synonym
cholesterol side-chain-cleaving enzyme activity synonym
cytochrome P-450(scc) activity synonym
Cyp11a1 synonym
cytochrome p450(scc) activity synonym
cytochrome P-450scc synonym
desmolase, steroid 20-22 synonym
cytochrome p450scc synonym
steroid 20-22 desmolase activity synonym
enzymes, cholesterol side-chain-cleaving synonym
steroid 20-22-lyase activity synonym