WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H+.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

8 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables

16 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0016757 glycosyltransferase activity Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
GO:0016758 hexosyltransferase activity Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor).
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0140103 catalytic activity, acting on a glycoprotein Catalysis of a biochemical reaction in which one of the substrates is a glycoprotein.
GO:0070085 glycosylation The covalent attachment and further modification of carbohydrate residues to a substrate molecule.
GO:0008417 fucosyltransferase activity Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
GO:0036071 N-glycan fucosylation The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains.
GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H+.
GO:0046921 alpha-(1->6)-fucosyltransferase activity Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage.
GO:0036065 fucosylation The covalent attachment of a fucosyl group to an acceptor molecule.

15 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0036071 GO:0008424
is_a GO:0140103 GO:0008424
is_a GO:0046921 GO:0008424
part of GO:0070085 GO:0008424
part of GO:0008152 GO:0008424
is_a GO:0140096 GO:0008424
is_a GO:0016757 GO:0008424
is_a GO:0008417 GO:0008424
is_a GO:0016758 GO:0008424
part of GO:0008150 GO:0008424
is_a GO:0016740 GO:0008424
part of GO:0036065 GO:0008424
is_a GO:0003674 GO:0008424
is_a GO:0003824 GO:0008424
part of GO:0009987 GO:0008424

10 Synonyms

Name Type
GDP-L-fucose--glycoprotein fucosyltransferase activity synonym
GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity synonym
glycoprotein fucosyltransferase activity synonym
GDPfucose-glycoprotein fucosyltransferase activity synonym
guanosine diphosphofucose--glycoprotein fucosyltransferase activity synonym
FucT synonym
GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity synonym
GDP-fucose--glycoprotein fucosyltransferase activity synonym
GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity synonym
GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity synonym