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Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0008518 folate:monoatomic anion antiporter activity GO

Namespace  molecular_function Obsolete  false
Description  Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

38 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0022857 transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0051234 establishment of localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein.
GO:0006811 monoatomic ion transport The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.
GO:0034220 monoatomic ion transmembrane transport A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.
GO:0055085 transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
GO:0015075 monoatomic ion transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other.
GO:0046943 carboxylic acid transmembrane transporter activity Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
GO:1903825 organic acid transmembrane transport The process in which an organic acid is transported across a membrane.
GO:0015711 organic anion transport The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
GO:1905039 carboxylic acid transmembrane transport The process in which carboxylic acid is transported across a membrane.
GO:0015849 organic acid transport The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0071705 nitrogen compound transport The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0008514 organic anion transmembrane transporter activity Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
GO:0046942 carboxylic acid transport The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
GO:0005342 organic acid transmembrane transporter activity Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage.
GO:0072349 modified amino acid transmembrane transporter activity Enables the transfer of modified amino acids from one side of a membrane to the other.
GO:0072337 modified amino acid transport The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015291 secondary active transmembrane transporter activity Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters.
GO:0022804 active transmembrane transporter activity Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
GO:0015297 antiporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
GO:0006835 dicarboxylic acid transport The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0042886 amide transport The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0098656 monoatomic anion transmembrane transport The process in which a monoatomic anion is transported across a membrane. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom.
GO:0008509 monoatomic anion transmembrane transporter activity Enables the transfer of a negatively charged ion from one side of a membrane to the other.

37 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0008509 GO:0008518
is_a GO:0015297 GO:0008518
is_a GO:0008517 GO:0008518
is_a GO:0015075 GO:0008518
part of GO:0009987 GO:0008518
is_a GO:0072349 GO:0008518
part of GO:0015849 GO:0008518
is_a GO:0022804 GO:0008518
part of GO:0006835 GO:0008518
part of GO:0051180 GO:0008518
part of GO:0006810 GO:0008518
part of GO:0006811 GO:0008518
part of GO:0055085 GO:0008518
part of GO:0034220 GO:0008518
part of GO:0098656 GO:0008518
part of GO:0015884 GO:0008518
is_a GO:0015291 GO:0008518
is_a GO:0008514 GO:0008518
is_a GO:0005342 GO:0008518
part of GO:0046942 GO:0008518
part of GO:0042886 GO:0008518
is_a GO:0046943 GO:0008518
part of GO:0006820 GO:0008518
part of GO:1903825 GO:0008518
is_a GO:0022857 GO:0008518
part of GO:0015711 GO:0008518
part of GO:0035461 GO:0008518
is_a GO:0005215 GO:0008518
is_a GO:0003674 GO:0008518
part of GO:0051179 GO:0008518

4 Synonyms

Name Type
folate:anion antiporter activity synonym
reduced folate carrier activity synonym
reduced folate transmembrane transporter activity synonym
reduced folate transporter synonym