WormMine: GOTerm GO:0008569 minus-end-directed microtubule motor activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: A motor activity that generates movement along a microtubule toward the minus end, driven by ATP hydrolysis.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

26 Ontology Annotations

15 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787	hydrolase activity	Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016817	hydrolase activity, acting on acid anhydrides	Catalysis of the hydrolysis of any acid anhydride.
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0016462	pyrophosphatase activity	Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.
GO:0017111	ribonucleoside triphosphate phosphatase activity	Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
GO:0016887	ATP hydrolysis activity	Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0140657	ATP-dependent activity	A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0003774	cytoskeletal motor activity	Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force).
GO:0120544	polypeptide conformation or assembly isomerase activity	Catalysis of a reaction that alters the conformation or assembly of a polypeptide.
GO:0016853	isomerase activity	Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GO:0120543	macromolecular conformation isomerase activity	Catalysis of a reaction that alters the macromolecular conformation of a molecule.
GO:0003777	microtubule motor activity	A motor activity that generates movement along a microtubule, driven by ATP hydrolysis.
GO:0008569	minus-end-directed microtubule motor activity	A motor activity that generates movement along a microtubule toward the minus end, driven by ATP hydrolysis.

16 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0003777	GO:0008569
has part	GO:0016887	GO:0008569
is_a	GO:0016853	GO:0008569
has part	GO:0016787	GO:0008569
has part	GO:0016818	GO:0008569
has part	GO:0016817	GO:0008569
is_a	GO:0003824	GO:0008569
is_a	GO:0003674	GO:0008569
is_a	GO:0003774	GO:0008569
has part	GO:0003674	GO:0008569
has part	GO:0017111	GO:0008569
has part	GO:0016462	GO:0008569
has part	GO:0003824	GO:0008569
is_a	GO:0120543	GO:0008569
is_a	GO:0120544	GO:0008569
is_a	GO:0140657	GO:0008569

7 Synonyms

• Name: ATP-dependent microtubule motor activity, minus-end-directed
• Type: synonym

• Name: dynein ATPase
• Type: synonym

• Name: ATP-dependent minus-end-directed microtubule motor activity
• Type: synonym

• Name: microtubule motor activity, minus-end-directed
• Type: synonym

• Name: kinesin ATP phosphohydrolase (minus-end-directed)
• Type: synonym

• Name: minus-end-directed kinesin ATPase activity
• Type: synonym

• Name: minus-end-directed ATP-dependent microtubule motor activity
• Type: synonym