WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0008700 (R,S)-4-hydroxy-2-oxoglutarate aldolase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate. Can act on both the (4R) and the (4S) enantiomers of 4-hydroxy-2-oxoglutarate.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

6 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016830 carbon-carbon lyase activity Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
GO:0016829 lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
GO:0016833 oxo-acid-lyase activity Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid.
GO:0008700 (R,S)-4-hydroxy-2-oxoglutarate aldolase activity Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate. Can act on both the (4R) and the (4S) enantiomers of 4-hydroxy-2-oxoglutarate.

5 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016833 GO:0008700
is_a GO:0016830 GO:0008700
is_a GO:0003674 GO:0008700
is_a GO:0016829 GO:0008700
is_a GO:0003824 GO:0008700

13 Synonyms

Name Type
2-keto-4-hydroxybutyrate aldolase activity synonym
2-keto-4-hydroxyglutarate aldolase activity synonym
2-oxo-4-hydroxyglutaric aldolase activity synonym
4-hydroxy-2-ketoglutarate aldolase activity synonym
2-keto-4-hydroxyglutaric aldolase activity synonym
2-oxo-4-hydroxyglutarate aldolase activity synonym
4-hydroxy-2-oxoglutarate glyoxylate-lyase activity synonym
DL-4-hydroxy-2-ketoglutarate aldolase activity synonym
4-hydroxy-2-ketoglutaric aldolase activity synonym
4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming) synonym
KHG-aldolase activity synonym
hydroxyketoglutarate aldolase activity synonym
hydroxyketoglutaric aldolase activity synonym