WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0009380 excinuclease repair complex GO

Namespace  cellular_component Obsolete  false
Description  Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

1 Ontology Annotations

Annotation Extension Qualifier
  part_of

8 Parents

Identifier Name Description
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0140535 intracellular protein-containing complex A protein-containing complex located intracellularly.
GO:1905348 endonuclease complex A protein complex which is capable of endonuclease activity.
GO:1990391 DNA repair complex A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO:1905347 endodeoxyribonuclease complex A protein complex which is capable of endodeoxyribonuclease activity.
GO:0009380 excinuclease repair complex Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap.

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:1905347 GO:0009380
is_a GO:1990391 GO:0009380
is_a GO:0140535 GO:0009380
is_a GO:0005575 GO:0009380
is_a GO:1905348 GO:0009380
is_a GO:0032991 GO:0009380
is_a GO:1902494 GO:0009380

2 Synonyms

Name Type
excinuclease ABC complex synonym
UvrABC excinuclease complex synonym