WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0010521 telomerase inhibitor activity GO

Namespace  molecular_function Obsolete  false
Description  Binds to and stops, prevents or reduces the activity of telomerase.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

1 Ontology Annotations

Annotation Extension Qualifier
  enables

17 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify a nucleic acid.
GO:0140097 catalytic activity, acting on DNA Catalytic activity that acts to modify DNA.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016772 transferase activity, transferring phosphorus-containing groups Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0016779 nucleotidyltransferase activity Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor).
GO:0003720 telomerase activity Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) using an internal RNA template that encodes the telomeric repeat sequence.
GO:0003964 RNA-directed DNA polymerase activity Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); RNA-template-directed extension of the 3'-end of a DNA strand by one deoxynucleotide at a time.
GO:0034061 DNA polymerase activity Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0004857 enzyme inhibitor activity Binds to and stops, prevents or reduces the activity of an enzyme.
GO:0140678 molecular function inhibitor activity A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0010521 telomerase inhibitor activity Binds to and stops, prevents or reduces the activity of telomerase.

20 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0004857 GO:0010521
negatively regulates GO:0003720 GO:0010521
negatively regulates GO:0140097 GO:0010521
negatively regulates GO:0016779 GO:0010521
negatively regulates GO:0140640 GO:0010521
is_a GO:0030234 GO:0010521
is_a GO:0140678 GO:0010521
has part GO:0003674 GO:0010521
regulates GO:0003674 GO:0010521
has part GO:0005488 GO:0010521
has part GO:0005515 GO:0010521
negatively regulates GO:0003824 GO:0010521
negatively regulates GO:0003964 GO:0010521
regulates GO:0003824 GO:0010521
is_a GO:0003674 GO:0010521
negatively regulates GO:0003674 GO:0010521
negatively regulates GO:0034061 GO:0010521
negatively regulates GO:0016740 GO:0010521
negatively regulates GO:0016772 GO:0010521
is_a GO:0098772 GO:0010521

0 Synonyms