WormMine: Phenotype WBPhenotype:0000165 cell fusion variant

• Description: Variations in the ability of two or more individual cells to form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes. Cell fusion is dependent on the merging of lipid bilayer membranes as well as cytoplasmic mixing.

6 RNAi

WormBase ID
WBRNAi00099045
WBRNAi00099047
WBRNAi00099046
WBRNAi00099048
WBRNAi00077961
WBRNAi00059901

0 RNAi Not Observed

5 Children

Identifier	Name	Description
WBPhenotype:0000297	rays fused	Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are joined to one another.
WBPhenotype:0000702	epithelial cell fusion failure	Any perturbation that renders epithelial cells incompetent at undergoing membrane fusion during development.
WBPhenotype:0000166	seam cell fusion variant	Variations in the ability of seam cells to fuse to form a continuous syncytium along the body wall late larval development, (separate from the hyp 7 syncytium), compared to control (WormAtlas). Hypodermal seam cells lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, and are required for alae formation.
WBPhenotype:0001433	precocious cell fusion	Two or more individual cells form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes at an earlier stage of development compared to comparable cells in control animals.
WBPhenotype:0001508	anchor cell fusion defective	Any perturbation that disrupts the fusion between the anchor cell and the surrounding utse syncytium. Such variations result in the loss of uterine-vulval connectivity and continuity.

1 Data Sets

• WormBaseAcedbConverter

1 Parents

Identifier	Name	Description
WBPhenotype:0000529	cell development variant	Any variation in the progression of a cell from when it is first formed to when it becomes a mature structure when compared to control animals.

8 Phenotype Allele

Public Name
sy5353
sy5411
sy5270
hy21
oj55
ay9
e1936
e1239

0 Phenotype Allele Not Observed

1 Synonyms

• Name: cell fusion abnormal