WormMine: Phenotype WBPhenotype:0000142 cell stress response variant

• Description: Variations in the activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress, compared to control. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

7 RNAi

WormBase ID
WBRNAi00063722
WBRNAi00063736
WBRNAi00063721
WBRNAi00063738
WBRNAi00106801
WBRNAi00063739
WBRNAi00063740

0 RNAi Not Observed

12 Children

Identifier	Name	Description
WBPhenotype:0000739	DNA damage response variant	Variations in the activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism, compared to control.
WBPhenotype:0000741	DNA damage checkpoint variant	Mitotic cells exhibit variations in the execution of cell-cycle arrest in response to DNA damage.
WBPhenotype:0001719	unfolded protein response variant	Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.
WBPhenotype:0000068	cellular oxidative stress response variant	Any variation in the state or activity of a cell (in terms of secretion, enzyme production, gene expression, etc.) in response to high levels of reactive oxygen species, compared to control.
WBPhenotype:0001485	ER stress response variant	Animals exhibit variations in their response to the presence of unfolded proteins in the endoplasmic reticulum (ER) or to other ER-related stressors compared to control.
WBPhenotype:0001324	cell ionizing radiation response variant	Cells exhibit variations in their response to ionizing radiation compared to that observed in control animals.
WBPhenotype:0001840	response to injury variant	Variations in the processes that restore integrity to a damaged tissue following an injury, compared to control.
WBPhenotype:0001725	cellular osmotic stress response variant	Cells exhibit variations in the response to osmotic stress compared to control. In C. elegans, exposure to stress-inducing osmotic conditions invokes cellular changes, including transcriptional up or down-regulation of genes.
WBPhenotype:0002434	mitochondrial stress response variant	Animals exhibit variations in their response to mitochondrial stress, compared to controls.
WBPhenotype:0000100	cell UV response variant	Cells exhibit variations in their response to ultraviolet radiation compared to that observed in control animals.
WBPhenotype:0000144	pathogen induced cell death increased	Animals exhibit an increase in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control.
WBPhenotype:0001486	unfolded protein accumulation	Animals accumulate unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria.

1 Data Sets

• WormBaseAcedbConverter

2 Parents

Identifier	Name	Description
WBPhenotype:0000067	organism stress response variant	Animals exhibit variations in response to stress stimuli compared to control animals.
WBPhenotype:0000585	cell homeostasis metabolism variant	Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the cell compared to control.

19 Phenotype Allele

Public Name
ks54
mg280
qm158
gk121
ky397
fr2
md290
km4
ag1
e205
km25
fr1
fr3
fr4
tm3036
tm2647
tm2654
ok3087
tm1817

7 Phenotype Allele Not Observed

Public Name
km2
km21
gk264
n498n1186
ju146
ok1052
nr2033

1 Synonyms

• Name: cell stress response abnormal