3 Children
Identifier | Name | Description |
---|---|---|
WBPhenotype:0000234 | dopamine deficient | Animals do not contain or are unable to maintain a the level of dopamine capable of initiating or maintaining dopamine-dependent cell activity compared to control animals. |
WBPhenotype:0000235 | dopamine synthesis defective | Animals are unable to carry out the chemical reactions and pathways resulting in the formation of dopamine. |
WBPhenotype:0000236 | dopamine catabolism defective | Animals are unable to carry outany chemical reaction or pathway resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. |
2 Parents
Identifier | Name | Description |
---|---|---|
WBPhenotype:0001518 | biogenic amine physiology variant | Any variation in the levels and/or localization of biogenic amines compared to control animals. |
WBPhenotype:0000221 | neurotransmitter metabolism variant | Animals exhibit variations in any chemical reaction or pathway involving neurotransmitters compared to control animals. Neurotransmitters are any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. |