WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Phenotype : WBPhenotype:0001422 endocytic transport defect

Description  Animals exhibit defects in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling.

56 RNAi

WormBase ID
WBRNAi00085170
WBRNAi00085171
WBRNAi00090868
WBRNAi00090870
WBRNAi00090869
WBRNAi00090872
WBRNAi00090871
WBRNAi00090874
WBRNAi00090873
WBRNAi00090876
WBRNAi00090875
WBRNAi00090878
WBRNAi00090877
WBRNAi00090880
WBRNAi00090879
WBRNAi00090962
WBRNAi00091026
WBRNAi00091105
WBRNAi00091159
WBRNAi00091158
WBRNAi00091161
WBRNAi00091160
WBRNAi00091163
WBRNAi00091162
WBRNAi00091165
WBRNAi00091164
WBRNAi00091167
WBRNAi00091166
WBRNAi00091169
WBRNAi00091168

1 RNAi Not Observed

WormBase ID
WBRNAi00085172

6 Children

Identifier Name Description
WBPhenotype:0001426 coelomocyte endocytosis defective Fluid-phase endocytosis by coelomocytes is less frequent or efficient compared to control.
WBPhenotype:0001514 synaptic vesicle endocytosis variant Variations in the uptake of a small membrane-bound organelle, filled with neurotransmitter(s) and/or neuropeptides, by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle compared to control(Wormatlas).
WBPhenotype:0001425 receptor mediated endocytosis defective Animals exhibit defects in the cell-mediated uptake of external materials via receptor activity. Receptor-mediated endocytosis ensures specificity of transport and generally occurs via clathrin-coated pits and vesicles. In C. elegans, this is often judged by the lack of yolk uptake in oocytes.
WBPhenotype:0001762 uptake of yolk defective Yolk is not taken up by oocytes in the same manner or to the same degree as observed for control animals. This often leads to an accumulation of yolk in the pseudocoelom.
WBPhenotype:0001860 endocytic recycling defective Variations in the directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport, compared to control.
WBPhenotype:0002561 homotypic endosome fusion defective Cells exhibit defects in the homotypic fusion of endosomes.

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Parents

Identifier Name Description
WBPhenotype:0001421 endocytic transport variant Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling compared to control.

7 Phenotype Allele

Public Name
dx2
mg455
ok538
kr15
zu437
ok1681
or552

1 Phenotype Allele Not Observed

Public Name
tm2332

0 Synonyms