16 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0032991 | protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
| GO:0005575 | cellular_component | A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
| GO:0110165 | cellular anatomical structure | A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. |
| GO:0071944 | cell periphery | The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. |
| GO:0098796 | membrane protein complex | Any protein complex that is part of a membrane. |
| GO:0016020 | membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. |
| GO:1990351 | transporter complex | A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. |
| GO:1902495 | transmembrane transporter complex | A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other. |
| GO:0005886 | plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| GO:0098797 | plasma membrane protein complex | Any protein complex that is part of the plasma membrane. |
| GO:0034702 | monoatomic ion channel complex | A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective monoatomic ion transport down its electrochemical gradient. |
| GO:0043235 | receptor complex | Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. |
| GO:0098802 | plasma membrane signaling receptor complex | Any protein complex that is part of the plasma membrane and which functions as a signaling receptor. |
| GO:0008328 | ionotropic glutamate receptor complex | A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. |
| GO:0098878 | neurotransmitter receptor complex | Any protein complex that is capable of functioning as a neurotransmitter receptor. |
| GO:0017146 | NMDA selective glutamate receptor complex | An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD. |
16 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| is_a | GO:0008328 | GO:0017146 |
| is_a | GO:1990351 | GO:0017146 |
| is_a | GO:0034702 | GO:0017146 |
| is_a | GO:0098797 | GO:0017146 |
| is_a | GO:0098796 | GO:0017146 |
| part of | GO:0016020 | GO:0017146 |
| is_a | GO:0043235 | GO:0017146 |
| is_a | GO:0005575 | GO:0017146 |
| part of | GO:0005886 | GO:0017146 |
| part of | GO:0110165 | GO:0017146 |
| is_a | GO:1902495 | GO:0017146 |
| part of | GO:0005575 | GO:0017146 |
| is_a | GO:0098878 | GO:0017146 |
| part of | GO:0071944 | GO:0017146 |
| is_a | GO:0098802 | GO:0017146 |
| is_a | GO:0032991 | GO:0017146 |
