WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Phenotype : WBPhenotype:0000885 engulfment variant

Description  Any variation in the removal of a cell corpse, by a neighboring cell or a phagocyte compared to control.

110 RNAi

WormBase ID
WBRNAi00097815
WBRNAi00098318
WBRNAi00078856
WBRNAi00078855
WBRNAi00078858
WBRNAi00078857
WBRNAi00087679
WBRNAi00087689
WBRNAi00087699
WBRNAi00087698
WBRNAi00087701
WBRNAi00087700
WBRNAi00087703
WBRNAi00087702
WBRNAi00087705
WBRNAi00087704
WBRNAi00087707
WBRNAi00087706
WBRNAi00087709
WBRNAi00087708
WBRNAi00087711
WBRNAi00087710
WBRNAi00087713
WBRNAi00087712
WBRNAi00087715
WBRNAi00087714
WBRNAi00087717
WBRNAi00087716
WBRNAi00087719
WBRNAi00087718

21 RNAi Not Observed

WormBase ID
WBRNAi00097600
WBRNAi00082784
WBRNAi00108422
WBRNAi00082786
WBRNAi00098454
WBRNAi00065427
WBRNAi00098296
WBRNAi00098455
WBRNAi00087621
WBRNAi00087620
WBRNAi00087623
WBRNAi00087622
WBRNAi00087625
WBRNAi00087624
WBRNAi00087627
WBRNAi00087626
WBRNAi00097592
WBRNAi00087629
WBRNAi00087628
WBRNAi00097596
WBRNAi00087630

4 Children

Identifier Name Description
WBPhenotype:0000243 engulfment failure by killer cell Removal of cell corpses through a dedicated engulfment pathway is defective.
WBPhenotype:0002394 phagosome sealing defective The closure of a phagosome does not occur and it remains connected with the plasma membrane, leaving the lumen open to the outside. Complete closure usually occurs once an apoptotic cell has been surrounded by an engulfing cell.
WBPhenotype:0001846 phagosome maturation defective Early phagosomes fail to undergo the maturation process following the ingestion of particulate material by phagocytosis; During maturation, phagosomes acquire markers of late endosomes and lysosomes.
WBPhenotype:0001808 cell corpse digestion variant The degradation of genomic and or cellular material of the corpse does not occur at the same rate or under the same conditions as observed in control animals undergoing cell death.

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Parents

Identifier Name Description
WBPhenotype:0000730 apoptosis variant Animals exhibit variations in any processes that influence the programmed cell death pathway. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell.

58 Phenotype Allele

Public Name
qx17
ok691
tm597
n4039
e1752
n1994
n1506
n1951
n1995
n2000
n2089
n2092
n2091
n691
e1735
tm1949
n1812
n2002
n3246
n1993
n1891
n1999
n2090
n2093
n1892
n2690
n1997
n1996
n1998
n2001

27 Phenotype Allele Not Observed

Public Name
tm1087
tm382
tm677
tm759
tm852
op216
ok393
mg144
ok525
gm103
mu28
tm3242
op309
ok742
ok976
e1189
e369
n777
n501
gk327
tm2429
tm2792
tm1060
tm1125
bp412
ok2561
bp242

2 Synonyms

Name Type
phagocytosis abnormal  
engulfment abnormal