WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

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Phenotype : WBPhenotype:0001587 actin organization biogenesis phenotype

Description  Animals exhibit variations in the formation and/or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas).

23 RNAi

WormBase ID
WBRNAi00091272
WBRNAi00091271
WBRNAi00091274
WBRNAi00091275
WBRNAi00091306
WBRNAi00101882
WBRNAi00061131
WBRNAi00065529
WBRNAi00092703
WBRNAi00061132
WBRNAi00098007
WBRNAi00079869
WBRNAi00078483
WBRNAi00112545
WBRNAi00112546
WBRNAi00112547
WBRNAi00112548
WBRNAi00077670
WBRNAi00077671
WBRNAi00077685
WBRNAi00083303
WBRNAi00083302
WBRNAi00114840

13 RNAi Not Observed

WormBase ID
WBRNAi00107859
WBRNAi00107860
WBRNAi00091280
WBRNAi00091308
WBRNAi00091307
WBRNAi00091310
WBRNAi00091309
WBRNAi00083312
WBRNAi00077796
WBRNAi00077795
WBRNAi00064285
WBRNAi00065666
WBRNAi00063832

4 Children

Identifier Name Description
WBPhenotype:0001354 actin cytoskeleton filament morphology phenotype Animals exhibit variations in the form, structure, composition or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas).
WBPhenotype:0001346 actin cytoskeleton dynamics phenotype Any variation in the dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins compared to control.
WBPhenotype:0002124 circumferential actin bundles disorganized The distribution or presence of actin in circumferential actin bundles (CFB) differs from that observed in control animals. Contraction of CFBs provide the driving force for epidermal elongation.
WBPhenotype:0002004 actomyosin contractility defective Animals exhibit defects in the flow rate or targeting of the cortical actomyosin network, which occurs during polarization as well as contraction of the contractile ring, compared to control animals.

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Parents

Identifier Name Description
WBPhenotype:0001345 cytoskeleton organization biogenesis variant Animals exhibit variations in the form, structure, composition or arrangement of any of the various filamentous elements that form the internal framework of cells, compared to control. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

9 Phenotype Allele

Public Name
r398
px47
s1309
su158
tm677
tm724
ok1523
gk27
it142

4 Phenotype Allele Not Observed

Public Name
su158
tk27
ok458
tm1362

2 Synonyms

Name Type
actin organization biogenesis variant  
actin organization biogenesis abnormal