WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Phenotype : WBPhenotype:0000631 drug response variant

Description  Any variation in the characteristic response(s) to drug(s) as defined by control animals.

3 RNAi

WormBase ID
WBRNAi00113924
WBRNAi00113926
WBRNAi00069754

2 RNAi Not Observed

WormBase ID
WBRNAi00113925
WBRNAi00110190

27 Children

Identifier Name Description
WBPhenotype:0001871 drug induced life span variant Life span of the animal is not influenced by drug exposure in the same manner as control animals.
WBPhenotype:0001872 drug induced locomotion variant Locomotion of the animal is not influenced by drug exposure in the same manner as control animals.
WBPhenotype:0001101 egg laying response to drug variant Characteristic response to drugs with respect to egg-laying behavior varies compared to control.
WBPhenotype:0000011 drug resistant Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Animals are not affected by exposure to the drug.
WBPhenotype:0000010 drug hypersensitive Animals respond to a specific drug at a lower concentration or a shorter exposure compared to control animals.
WBPhenotype:0000845 levamisole response variant Animals exhibit variations in the response to the addition of levamisole compared to that observed in control animals. Levamisole is a cholinergic agonist.
WBPhenotype:0001573 nicotine response variant Animals exhibit variations in the response to the addition of nicotine compared to that observed in control animals. Nicotine is a cholinergic agonist.
WBPhenotype:0002109 drug susceptible Animals are affected by exposure to the drug.
WBPhenotype:0000681 DMPP response variant Animals exhibit variations in their response to DMPP compared to that observed in control animals.
WBPhenotype:0000359 tunicamycin response variant Animals exhibit variations in the response to the addition of tunicamycin compared to that observed in control animals. Tunicamycin induces the unfolded protein response.
WBPhenotype:0001842 drug withdrawal response variant Any variation in the state or activity of an organism as a result of abrupt discontinuation or decreased dosage of a drug, compared to control.
WBPhenotype:0001232 serotonin response variant Animals exhibit variations in the response to the addition of serotonin compared to that observed in control animals. Serotonin is a monoamine neurotransmitter.
WBPhenotype:0000555 drug adaptation variant Animals show variations in their decreased responsiveness after prolonged or repeated exposure to a drug compared to that in control.
WBPhenotype:0001854 benomyl response variant Animals exhibit variations in their response to the microtubule-depolymerizing drug benomyl, compared to that observed in control animals.
WBPhenotype:0001856 ivermectin response variant Animals exhibit variations in their response to ivermectin, an agonist of glutamate-gated chloride channels, compared to that observed in control animals.
WBPhenotype:0001783 ligand gated channel activity variant Animals exhibit variations in the actions of a channel that catalyses the transmembrane transfer of a cation when acetylcholine has been bound by the channel complex or one of its constituent parts compared to control animals.
WBPhenotype:0002058 pore forming toxin response variant Animals are not affected to the same degree as control animals under similar conditions of pore forming toxin exposure.
WBPhenotype:0002047 muscimol response variant Animals exhibit variations in their response to muscimol compared to that observed in control animals. Muscimol is a GABA-A receptor agonist.
WBPhenotype:0000558 calcium channel modulator response variant Animals exhibit variations in their response to specific calcium channel modulators compared to that observed in control animals.
WBPhenotype:0002049 abamectin repsonse variant Animals are not affected to the same degree as control animals under similar conditions of abamectin exposure.
WBPhenotype:0001290 acetylcholinesterase inhibitor response variant Animals exhibit variations in their response to a specific acetylcholinesterase inhibitor compared to that observed in control animals.
WBPhenotype:0002384 xenotoxicity suppressor Animals are resistant to the toxicity of an anti-infective xenobiotic such as R24. Such small molecules protect the host from bacterial infection by inducing antibacterial immune responses via the p38 MAPK pathway. These molecules tend to have toxic effects in addition to immunostimulatory activity.
WBPhenotype:0001878 hydroxyurea response variant Animals exhibit variations in the response to the addition of hydroxyurea compared to that observed in control animals. Hydroxyurea stops DNA from being replicated.
WBPhenotype:0001337 adrenergic receptor antagonist response variant Animals exhibit variations in their response to a specific adrenergic receptor antagonist compared to that observed in control animals.
WBPhenotype:0001614 anticonvulsant response variant Animals exhibit variations in their response to a specific anticonvulsant compared to that observed in control animals.
WBPhenotype:0001598 inhibitor of serotonin uptake variant Treatment with inhibitors of serotonin reuptake does not elicit the same response as observed for control animals.
WBPhenotype:0000627 anesthetic response variant Animals exhibit variations in their response to a specific anesthetic compared to that observed in control animals.

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Parents

Identifier Name Description
WBPhenotype:0000523 chemical response variant Animals exhibit variations in their response to a specific chemical compared to that observed in control animals.

51 Phenotype Allele

Public Name
rh40
rh80
rh148
rh326
mgDf50
t1550
ns204
n592
n478
md176
n586
n488
md1971
n602
n587
n162
n549
n611
n585
ad806
n686
n570
n170
n155
n742
n171
e1368
n3246
gm103
n3314

49 Phenotype Allele Not Observed

Public Name
mg280
sa734
mgDf50
ok326
n488
nj77
vs100
ky5
mgDf47
e1372
nu62
e1370
n1994
n1812
n1993
e245
p1152
e1112
ad1650
pk17
ky400
mu28
ok103
km21
e113
e53
e876
ok1995
ok2007
ad1774

1 Synonyms

Name Type
drug response abnormal