WormMine: Phenotype WBPhenotype:0001650 germ cell death response to 5 FU resistant

• Description: Germ cell death fails in response to the concentration of 5-FU that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, in addition to cell death, 5-FU exposed animals exhibit condensed germ cell nuclei or unhealthy nuclei.

0 RNAi

0 RNAi Not Observed

0 Children

1 Data Sets

• WormBaseAcedbConverter

1 Parents

Identifier	Name	Description
WBPhenotype:0001649	Fluorouracil resistant	Animals fail to respond to the concentration of Fluorouracil (5-FU) that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. Elegans Fluorouracil induces germ cell death, inhibits embryogenesis and inhibits larval growth (depending on dose) in control animals.

3 Phenotype Allele

Public Name
n1162
jg1
jg9

3 Phenotype Allele Not Observed

Public Name
n717
n1950
ok238

0 Synonyms