WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Phenotype : WBPhenotype:0001100 early embryonic lethal

Description  Animal dies prior to the gastrulation stage of embryogenesis.

54 RNAi

WormBase ID
WBRNAi00092482
WBRNAi00077491
WBRNAi00093049
WBRNAi00066419
WBRNAi00065645
WBRNAi00069901
WBRNAi00066435
WBRNAi00087517
WBRNAi00087516
WBRNAi00093801
WBRNAi00114367
WBRNAi00093797
WBRNAi00093798
WBRNAi00114369
WBRNAi00082128
WBRNAi00078185
WBRNAi00082129
WBRNAi00065825
WBRNAi00078405
WBRNAi00078404
WBRNAi00089523
WBRNAi00087466
WBRNAi00106663
WBRNAi00066338
WBRNAi00066402
WBRNAi00066404
WBRNAi00087467
WBRNAi00112253
WBRNAi00087518
WBRNAi00063614

4 RNAi Not Observed

WormBase ID
WBRNAi00092494
WBRNAi00111187
WBRNAi00092493
WBRNAi00111188

24 Children

Identifier Name Description
WBPhenotype:0001178 egg integrity defective early emb The structure of the egg is impaired, flawed or no longer intact.
WBPhenotype:0001118 cell position defective early emb Cell position is abnormal in the early embryo.
WBPhenotype:0001077 chromosome segregation variant karyomeres early emb Karyomeres in AB or P1 often accompanied by weak/thin wobbly spindle.
WBPhenotype:0001034 pronuclear nuclear appearance defective early emb The morphology of pronuclei and nuclei are defective in the early embryo. In C. elegans, this defect is often characterized by pronuclei and nuclei that are small or missing altogether and are often accompanied by spindle defects.
WBPhenotype:0000748 asymmetric cell division defective early emb Symmetric (PAR-like) divisions or excessive posterior displacement (zyg-8 like phenotypes).
WBPhenotype:0001167 pseudocleavage defective early emb Pseudocleavage is atypical in the inviable one-cell embryo.
WBPhenotype:0000759 spindle defective early emb Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubules and associated molecules that form between opposite poles of a eukaryotic cell during a cell cycle.
WBPhenotype:0000044 egg size defective early emb Egg is smaller or larger compared to eggs of control animals.
WBPhenotype:0001135 embryonic morphology defective early emb Animals exhibit defects in the form, structure or composition of any of its parts during the early embryonic stage.
WBPhenotype:0001185 embryonic developmental delay early emb The developmental progression of an early embryo over time, from its formation to its mature structure is delayed compared to control.
WBPhenotype:0001078 cytokinesis defective early emb Cytokinesis is abnormal in the first or second stages of cell division.
WBPhenotype:0001114 cell cycle defective early emb The progression of biochemical and morphological processes that occur during successive replication or nuclear replication events is disrupted during the early embryonic stage.
WBPhenotype:0000040 one cell arrest early emb Embryos fail to divide and arrest as one-cell embryos.
WBPhenotype:0001043 interphase entry defective early emb Embryos do not enter or take longer to enter first interphase compared to control.
WBPhenotype:0000771 centrosome attachment defective early emb Centrosomes detach from the male pronucleus.
WBPhenotype:0001110 aster defective early emb Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores.
WBPhenotype:0001041 meiosis defective early emb Animals exhibit defects in the progression of meiosis which ultimately result in embryonic lethality.
WBPhenotype:0001044 cortical dynamics defective early emb Little/no cortical ruffling or pseudocleavage furrow, or excessive cortical activity. In C. elegans, this is often characterized at the two-cell stage.
WBPhenotype:0001007 other abnormality early emb Unclassified abnormality in the inviable one- to four-cell embryo.
WBPhenotype:0000767 integrity of membranous organelles defective early emb Sparse or enlarged yolk granules.
WBPhenotype:0000769 cytoplasmic appearance defective early emb Embryos exhibit defects in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control embryos.
WBPhenotype:0001147 polar body defective early emb Polar bodies are abnormal in the inviable one- to four-cell embryo.
WBPhenotype:0001134 Aba ABp division axis defective early emb ABa or ABp divide in the wrong orientation.
WBPhenotype:0001117 cell cell contacts abnormal early emb Cell-cell contacts are abnormal in the early embryo.

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Parents

Identifier Name Description
WBPhenotype:0000050 embryonic lethal Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.

9 Phenotype Allele

Public Name
s1727
yn5
tm1547
oj35
oj29
tm3175
or362
hc57
hc62

1 Phenotype Allele Not Observed

Public Name
xoe4

1 Synonyms

Name Type
Emb