WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Phenotype : WBPhenotype:0000011 drug resistant

Description  Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Animals are not affected by exposure to the drug.

4 RNAi

WormBase ID
WBRNAi00078473
WBRNAi00112311
WBRNAi00108456
WBRNAi00108455

1 RNAi Not Observed

WormBase ID
WBRNAi00108457

22 Children

Identifier Name Description
WBPhenotype:0001507 Bacillus thuringiensis toxin resistant Animals fail to be affected by toxins produced by Bacillus thuringiensis (Bt toxins) in the same manner as control animals.
WBPhenotype:0002060 pore forming toxin resistant Animals fail to respond to the concentration of pore forming toxins that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0001289 acetylcholinesterase inhibitor resistant Animals fail to respond to the concentration of acetylcholinesterase inhibitor that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0002053 ivermectin resistant Animals fail to respond to or exhibit an attenuated response to ivermectin under conditions that elicits a response in control animals.
WBPhenotype:0000252 caffeine resistant Animals fail to respond to the concentration of caffeine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0001204 muscimol resistant Animals fail to respond to the concentration of muscimol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0001839 phorbol ester resistant Animals fail to respond to the concentration of phorbol esters that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Phorbol esters such as PMA act as DAG mimetics.
WBPhenotype:0000024 serotonin resistant Animals fail to respond to the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0000340 imipramine resistant Animals fail to respond to the concentration of imipramine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0000487 colchicine resistant Animals fail to respond to the concentration of colchicine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0002077 dopamine resistant Animals fail to respond to the concentration of a dopamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0000089 alpha amanitin resistant Animals fail to respond to the concentration of alpha amanitin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0001578 cholinergic agonist resistant Animals fail to respond to the concentration of cholinergic agonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0001649 Fluorouracil resistant Animals fail to respond to the concentration of Fluorouracil (5-FU) that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. Elegans Fluorouracil induces germ cell death, inhibits embryogenesis and inhibits larval growth (depending on dose) in control animals.
WBPhenotype:0000381 serotonin reuptake inhibitor resistant Animals fail to respond to the concentration of serotonin reuptake inhibitors that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0000790 fluoxetine resistant Animals fail to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0000489 chloroquine resistant Animals fail to respond to the concentration of chloroquine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0000560 calcium channel modulator resistant Animals fail to respond to the concentration of calcium channel modulators that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0000009 anesthetic resistant Animals fail to respond to the concentration of anesthetic that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0000331 inhibitors of na k atpase resistant Animals fail to respond to the concentration of sodium potassium ATPase antagonists that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0001601 biogenic amine receptor antagonist resistant Animals fail to respond to the concentration of biogenic amine receptor antagonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0001615 anticonvulsant resistant Animals fail to respond to the concentration of compounds that act as anticonvulsants that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Parents

Identifier Name Description
WBPhenotype:0000631 drug response variant Any variation in the characteristic response(s) to drug(s) as defined by control animals.

93 Phenotype Allele

Public Name
ok285
sa330
ut73
ut5
nj77
n582
ad695
ad1006
tr70
tr69
tr74
tr73
tr72
tr71
tr78
tr77
tr76
tr75
tr85
tr84
tr81
tr79
tr89
tr88
tr87
tr86
tr93
tr92
tr91
tr90

0 Phenotype Allele Not Observed

0 Synonyms