WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0030121 AP-1 adaptor complex GO

Namespace  cellular_component Obsolete  false
Description  A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

15 Ontology Annotations

Annotation Extension Qualifier
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39 Parents

Identifier Name Description
GO:0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005737 cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0005622 intracellular anatomical structure A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.
GO:0110165 cellular anatomical structure A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
GO:0043227 membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0043231 intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0098796 membrane protein complex Any protein complex that is part of a membrane.
GO:0012505 endomembrane system A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.
GO:0098588 bounding membrane of organelle The lipid bilayer that forms the outer-most layer of an organelle.
GO:0031090 organelle membrane A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
GO:0005794 Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
GO:0031410 cytoplasmic vesicle A vesicle found in the cytoplasm of a cell.
GO:0097708 intracellular vesicle Any vesicle that is part of the intracellular region.
GO:0031982 vesicle Any small, fluid-filled, spherical organelle enclosed by membrane.
GO:0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle.
GO:0012506 vesicle membrane The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
GO:0005798 Golgi-associated vesicle Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.
GO:0030133 transport vesicle Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
GO:0030658 transport vesicle membrane The lipid bilayer surrounding a transport vesicle.
GO:0030662 coated vesicle membrane The lipid bilayer surrounding a coated vesicle.
GO:0030135 coated vesicle Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.
GO:0030660 Golgi-associated vesicle membrane The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.
GO:0012510 trans-Golgi network transport vesicle membrane The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell.
GO:0030140 trans-Golgi network transport vesicle A vesicle that mediates transport between the trans-Golgi network and other parts of the cell.
GO:0030665 clathrin-coated vesicle membrane The lipid bilayer surrounding a clathrin-coated vesicle.
GO:0030136 clathrin-coated vesicle A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.

41 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0030130 GO:0030121
is_a GO:0030131 GO:0030121
part of GO:0048475 GO:0030121
is_a GO:0005575 GO:0030121
part of GO:0110165 GO:0030121
part of GO:0005622 GO:0030121
part of GO:0016020 GO:0030121
part of GO:0098796 GO:0030121
part of GO:0012510 GO:0030121
part of GO:0030140 GO:0030121
part of GO:0030120 GO:0030121
part of GO:0097708 GO:0030121
part of GO:0030660 GO:0030121
part of GO:0005794 GO:0030121
is_a GO:0030119 GO:0030121
part of GO:0031410 GO:0030121
part of GO:0030662 GO:0030121
part of GO:0030125 GO:0030121
part of GO:0030665 GO:0030121
part of GO:0043231 GO:0030121
is_a GO:0032991 GO:0030121
part of GO:0005737 GO:0030121
part of GO:0098588 GO:0030121
part of GO:0005575 GO:0030121
part of GO:0005798 GO:0030121
part of GO:0031090 GO:0030121
is_a GO:0098796 GO:0030121
part of GO:0043229 GO:0030121
part of GO:0043227 GO:0030121
part of GO:0032991 GO:0030121

3 Synonyms

Name Type
HA1 synonym
AP-1 related adapter complex synonym
HA1 clathrin adaptor synonym