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GO:0032991
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protein-containing complex
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A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
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GO:0005737
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cytoplasm
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The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
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GO:0005575
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cellular_component
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A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
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GO:0005622
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intracellular anatomical structure
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A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. |
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GO:0110165
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cellular anatomical structure
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A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. |
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GO:0043227
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membrane-bounded organelle
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Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
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GO:0043226
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organelle
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Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. |
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GO:0043229
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intracellular organelle
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Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
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GO:0043231
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intracellular membrane-bounded organelle
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Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
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GO:0098796
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membrane protein complex
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Any protein complex that is part of a membrane. |
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GO:0012505
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endomembrane system
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A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. |
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GO:0016020
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membrane
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A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. |
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GO:0098588
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bounding membrane of organelle
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The lipid bilayer that forms the outer-most layer of an organelle. |
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GO:0031090
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organelle membrane
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A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. |
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GO:0031410
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cytoplasmic vesicle
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A vesicle found in the cytoplasm of a cell. |
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GO:0097708
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intracellular vesicle
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Any vesicle that is part of the intracellular region. |
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GO:0031982
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vesicle
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Any small, fluid-filled, spherical organelle enclosed by membrane. |
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GO:0030659
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cytoplasmic vesicle membrane
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The lipid bilayer surrounding a cytoplasmic vesicle. |
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GO:0012506
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vesicle membrane
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The lipid bilayer surrounding any membrane-bounded vesicle in the cell. |
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GO:0030133
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transport vesicle
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Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell. |
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GO:0030658
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transport vesicle membrane
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The lipid bilayer surrounding a transport vesicle. |
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GO:0012507
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ER to Golgi transport vesicle membrane
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The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi. |
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GO:0030134
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COPII-coated ER to Golgi transport vesicle
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A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport). |
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GO:0030662
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coated vesicle membrane
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The lipid bilayer surrounding a coated vesicle. |
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GO:0030135
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coated vesicle
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Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins. |
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GO:0030117
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membrane coat
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Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules. |
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GO:0048475
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coated membrane
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A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes. |
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GO:0030120
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vesicle coat
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A membrane coat found on a coated vesicle. |
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GO:0030127
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COPII vesicle coat
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One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state. |
