WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0030251 guanylate cyclase inhibitor activity GO

Namespace  molecular_function Obsolete  false
Description  Binds to and stops, prevents or reduces the activity of guanylate cyclase.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

16 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0005515 protein binding Binding to a protein.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0004857 enzyme inhibitor activity Binds to and stops, prevents or reduces the activity of an enzyme.
GO:0140678 molecular function inhibitor activity A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0016829 lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
GO:0009975 cyclase activity Catalysis of a ring closure reaction.
GO:0016849 phosphorus-oxygen lyase activity Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
GO:0004383 guanylate cyclase activity Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.
GO:0010851 cyclase regulator activity Binds to and modulates the activity of an enzyme that catalyzes a ring closure reaction.
GO:0030249 guanylate cyclase regulator activity Modulates the activity of guanylate cyclase.
GO:0010852 cyclase inhibitor activity Binds to and decreases the activity of an enzyme that catalyzes a ring closure reaction.
GO:0030251 guanylate cyclase inhibitor activity Binds to and stops, prevents or reduces the activity of guanylate cyclase.

23 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0030249 GO:0030251
is_a GO:0010852 GO:0030251
negatively regulates GO:0004383 GO:0030251
regulates GO:0004383 GO:0030251
regulates GO:0009975 GO:0030251
regulates GO:0016829 GO:0030251
is_a GO:0010851 GO:0030251
regulates GO:0016849 GO:0030251
negatively regulates GO:0016829 GO:0030251
negatively regulates GO:0016849 GO:0030251
negatively regulates GO:0003674 GO:0030251
regulates GO:0003674 GO:0030251
negatively regulates GO:0009975 GO:0030251
is_a GO:0003674 GO:0030251
is_a GO:0004857 GO:0030251
regulates GO:0003824 GO:0030251
is_a GO:0098772 GO:0030251
negatively regulates GO:0003824 GO:0030251
has part GO:0005515 GO:0030251
is_a GO:0140678 GO:0030251
has part GO:0003674 GO:0030251
has part GO:0005488 GO:0030251
is_a GO:0030234 GO:0030251

0 Synonyms