WormMine: GOTerm GO:0030337 DNA polymerase processivity factor activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

14 Ontology Annotations

15 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740	transferase activity	Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0140640	catalytic activity, acting on a nucleic acid	Catalytic activity that acts to modify a nucleic acid.
GO:0140097	catalytic activity, acting on DNA	Catalytic activity that acts to modify DNA.
GO:0005488	binding	The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016772	transferase activity, transferring phosphorus-containing groups	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0005515	protein binding	Binding to a protein.
GO:0098772	molecular function regulator activity	A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0016779	nucleotidyltransferase activity	Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor).
GO:0034061	DNA polymerase activity	Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).
GO:0140677	molecular function activator activity	A molecular function regulator that activates or increases the activity of its target via non-covalent binding that does not result in covalent modification to the target.
GO:0030234	enzyme regulator activity	Binds to and modulates the activity of an enzyme.
GO:0008047	enzyme activator activity	Binds to and increases the activity of an enzyme.
GO:0030337	DNA polymerase processivity factor activity	An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it.

18 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
positively regulates	GO:0034061	GO:0030337
is_a	GO:0008047	GO:0030337
positively regulates	GO:0003674	GO:0030337
has part	GO:0005515	GO:0030337
is_a	GO:0140677	GO:0030337
is_a	GO:0030234	GO:0030337
regulates	GO:0003674	GO:0030337
positively regulates	GO:0016772	GO:0030337
has part	GO:0003674	GO:0030337
has part	GO:0005488	GO:0030337
positively regulates	GO:0016740	GO:0030337
positively regulates	GO:0003824	GO:0030337
is_a	GO:0003674	GO:0030337
positively regulates	GO:0016779	GO:0030337
regulates	GO:0003824	GO:0030337
positively regulates	GO:0140097	GO:0030337
is_a	GO:0098772	GO:0030337
positively regulates	GO:0140640	GO:0030337

2 Synonyms

• Name: sliding clamp
• Type: synonym

• Name: processivity clamp
• Type: synonym