WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0030342 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol).

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

7 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0004497 monooxygenase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
GO:0008395 steroid hydroxylase activity Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.
GO:0070576 vitamin D 24-hydroxylase activity Catalysis of the hydroxylation of C-24 of any form of vitamin D.
GO:0030342 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol).

6 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0070576 GO:0030342
is_a GO:0008395 GO:0030342
is_a GO:0003674 GO:0030342
is_a GO:0003824 GO:0030342
is_a GO:0016491 GO:0030342
is_a GO:0004497 GO:0030342

2 Synonyms

Name Type
calcitriol 24-hydroxylase activity synonym
1,25-(OH)2D3 24-hydroxylase activity synonym