WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Phenotype : WBPhenotype:0000615 cilia morphology variant

Description  Animals exhibit variations in the structure or organization of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals. In C. elegans, cilia are classified as channel cilia or wing cilia depending on their placement within the sensillum. Channel cilia of control animals are cylindrical, extend into the sensillum pore and are exposed to the outside. Wing cilia of control animals vary in shape, are embedded in the sensillum sheath cell and are not typically refractory to dyes indicating exposure to the outside.

1 RNAi

WormBase ID
WBRNAi00113377

0 RNAi Not Observed

5 Children

Identifier Name Description
WBPhenotype:0000310 cilia absent Neurons lack the finger-like dendritic projections, which are observed extending from similar cells in control animals.
WBPhenotype:0001249 amphid channel cilia morphology variant Animals exhibit variations in the structure or composition of the dendritic projections of the amphid sensory neurons that traverse the sensillum pore to connect with the outside of the animal, compared to that observed in control animals. In C. elegans, amphid channel cilia morphology is frequently assayed by dye-filling experiments using FITC, DiI or DiO.
WBPhenotype:0000262 axoneme morphology variant Animals exhibit variations in the structure or composition of the microtubule-based fibrillar bundle (axoneme) that makes up the core of the middle part of the cilium (in a pattern of nine doublet microtubules attached to the membrane and a variable number of smaller singlet microtubules occupying the center). In C. elegans, the axoneme microtubules are arranged in a pattern of nine doublets attached to the membrane with seven smaller singlet microtubules occupying the center.
WBPhenotype:0001248 wing cilia morphology variant Animals exhibit variations in the structure or organization of the microtuble-based projections that in control animals invaginate individually into the sheath cell of the neuronal sensillum rather than projecting through the socket cell to the outside. In C. elegans, the cilia of each wing cell has its own unique shape and as they are not exposed to the outside, they do not typically take up dyes.
WBPhenotype:0002470 cilia length variant Animals exhibit variations in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals.

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Parents

Identifier Name Description
WBPhenotype:0001526 ciliated neuron morphology variant Animals exhibit variations in the structure or organization of any one of the specialized sensory receptor cells of the nervous system that compared to control animals. In C. elegans, these specialized cells are characterized as having axoneme containing dendritic projections emanating from their cell body.
WBPhenotype:0002089 cell component morphology variant Any variation in the form or composition of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles.

39 Phenotype Allele

Public Name
tm324
ok200
ju639
ok1170
ok1177
mn400
mn335
m160
tm4024
e1387
ut306
jhu598
e1124
e1033
e1805
e1810
p811
p808
p802
n1540
m184
mn397
p813
e398
ot85
ok676
ok169
e1809
gk477
gk513

10 Phenotype Allele Not Observed

Public Name
tm313
sy552
ok3203
tm4024
ky4
my8
ok169
gj204
p675
tm2409

2 Synonyms

Name Type
defective dye filling of cilia  
cilia morphology abnormal