WormMine: Phenotype WBPhenotype:0000028 RNA processing variant

• Description: Variations in the processes involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules compared to control.

3 RNAi

WormBase ID
WBRNAi00093855
WBRNAi00110708
WBRNAi00063100

0 RNAi Not Observed

7 Children

Identifier	Name	Description
WBPhenotype:0001538	mRNA surveillance defective	Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia.
WBPhenotype:0001834	mRNA splicing variant	Variations in the processes regulating the excision of intervening introns from the primary mRNA transcript, compared to control.
WBPhenotype:0001807	alternative splicing variant	Any variation in the process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition compared to control.
WBPhenotype:0002155	pre miRNA processing defective	The production of mature miRNA from pre-miRNA is significantly deficient compared to controls. Deficiencies in this process can result in the accumulation of pre-miRNA species and or the absence or smaller amount of mature miRNA compared to controls.
WBPhenotype:0001826	RNA degradation variant	Variations in the regulated breakdown of RNA species via the action of cellular enzymes (RNases) compared to control.
WBPhenotype:0002153	dsRNA processing defective	The production of silencing RNA from dsRNA is significantly deficient compared to controls. Deficiencies in this process can result in a defective RNAi response compared to controls.
WBPhenotype:0002254	three prime target RNA uridylation reduced	Three-prime (3') uridylation of mRNA targeted for silencing does not occur at the same rate or extent of targeted mRNA in control animals.

1 Data Sets

• WormBaseAcedbConverter

2 Parents

Identifier	Name	Description
WBPhenotype:0000113	RNA expression variant	Variations in the biogenesis and stability of any class of RNA molecules (rRNAs, miRNAs, tRNAs etc) compared to control.
WBPhenotype:0001827	RNA metabolism variant	Variations in any process that involves the maintenance, biosynthesis or accumulation of RNA in the organism compared to control.

9 Phenotype Allele

Public Name
tm367
gv42
ne3364
na27
tm2715
tm2802
op259
tm1297
ne3361

1 Phenotype Allele Not Observed

Public Name
tm5166

1 Synonyms

• Name: RNA processing abnormal