GO:0032991
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protein-containing complex
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A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
GO:0005575
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cellular_component
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A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
GO:0005622
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intracellular anatomical structure
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A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. |
GO:0110165
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cellular anatomical structure
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A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. |
GO:0043226
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organelle
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Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. |
GO:0043229
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intracellular organelle
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Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
GO:0043228
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membraneless organelle
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Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. |
GO:0043232
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intracellular membraneless organelle
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Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. |
GO:0005694
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chromosome
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A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. |
GO:0099080
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supramolecular complex
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A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber. |
GO:0000940
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outer kinetochore
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The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions. |
GO:0000776
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kinetochore
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A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. |
GO:0000775
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chromosome, centromeric region
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The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. |
GO:0000779
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condensed chromosome, centromeric region
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The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. |
GO:0098687
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chromosomal region
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Any subdivision of a chromosome along its length. |
GO:0000793
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condensed chromosome
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A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. |
GO:0031262
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Ndc80 complex
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An essential outer kinetochore complex involved in the attachment of microtubule ends to the chromosomes during mitosis. |