WormMine: GOTerm GO:0031428 box C/D methylation guide snoRNP complex GO

• Namespace: cellular_component
• Obsolete: false
• Description: A ribonucleoprotein complex containing a box C/D type RNA that is capable of ribose-2'-O-methylation of target RNAs. Box C/D type RNAs are widespread in eukaryotes and in Archaea, suggesting that an RNA-based guide mechanism for directing specific RNA 2'-O-ribose methylations was present in the common ancestor of Archaea and Eukarya.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

8 Ontology Annotations

6 Parents

Identifier	Name	Description
GO:0032991	protein-containing complex	A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
GO:0005575	cellular_component	A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
GO:0005732	sno(s)RNA-containing ribonucleoprotein complex	A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family and associated proteins. Many are involved in a step of processing of rRNA molecules: cleavage, 2'-O-methylation, or pseudouridylation, but other RNA types can be targets as well. The majority fall into one of two classes, box C/D type or box H/ACA type, which are conserved across eukaryotes and archaea. Other members include the telomerase RNA and the ribonuclease MRP RNA.
GO:1990904	ribonucleoprotein complex	A macromolecular complex that contains both RNA and protein molecules.
GO:0170049	box C/D RNP complex	A ribonucleoprotein complex consisting of a box C/D type snRNA and three (Archaea) or four (Eukaryotes) core proteins that have diverse functions, including site-specific methylation of rRNA and processing rRNA.
GO:0031428	box C/D methylation guide snoRNP complex	A ribonucleoprotein complex containing a box C/D type RNA that is capable of ribose-2'-O-methylation of target RNAs. Box C/D type RNAs are widespread in eukaryotes and in Archaea, suggesting that an RNA-based guide mechanism for directing specific RNA 2'-O-ribose methylations was present in the common ancestor of Archaea and Eukarya.

5 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0170049	GO:0031428
is_a	GO:0005575	GO:0031428
is_a	GO:1990904	GO:0031428
is_a	GO:0032991	GO:0031428
is_a	GO:0005732	GO:0031428

5 Synonyms

• Name: box C/D snoRNP complex
• Type: synonym

• Name: box C/D snoRNP ribose 2'-O methylase complex
• Type: synonym

• Name: box C/D small nucleolar ribonucleoprotein complex
• Type: synonym

• Name: box C/D snoRNP ribose-2'-O-methyltransferase complex
• Type: synonym

• Name: box C/D sRNP complex
• Type: synonym