22 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:1902494 | catalytic complex | A protein complex which is capable of catalytic activity. |
| GO:0032991 | protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
| GO:0005575 | cellular_component | A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
| GO:0005622 | intracellular anatomical structure | A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. |
| GO:0110165 | cellular anatomical structure | A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. |
| GO:0140513 | nuclear protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. |
| GO:0043227 | membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| GO:0043226 | organelle | Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. |
| GO:0005634 | nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| GO:0043229 | intracellular organelle | Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
| GO:0043231 | intracellular membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
| GO:0031974 | membrane-enclosed lumen | The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen. |
| GO:0031981 | nuclear lumen | The volume enclosed by the nuclear inner membrane. |
| GO:0070013 | intracellular organelle lumen | An organelle lumen that is part of an intracellular organelle. |
| GO:0043233 | organelle lumen | The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen. |
| GO:0005730 | nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| GO:0043228 | membraneless organelle | Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. |
| GO:0043232 | intracellular membraneless organelle | Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. |
| GO:0005732 | sno(s)RNA-containing ribonucleoprotein complex | A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family and associated proteins. Many are involved in a step of processing of rRNA molecules: cleavage, 2'-O-methylation, or pseudouridylation, but other RNA types can be targets as well. The majority fall into one of two classes, box C/D type or box H/ACA type, which are conserved across eukaryotes and archaea. Other members include the telomerase RNA and the ribonuclease MRP RNA. |
| GO:1990904 | ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
| GO:0031429 | box H/ACA snoRNP complex | A box H/ACA small nucleolar ribonucleoprotein complex located in the nucleolus that catalyzes pseudouridylation of ribosomal RNA residues. The complex is composed of four different core proteins that assemble onto a H/ACA guide RNA scaffold that identifies specific uridines in rRNA for modification during ribosome synthesis. |
| GO:0072588 | box H/ACA RNP complex | A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex. |
22 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| is_a | GO:0140513 | GO:0031429 |
| part of | GO:0005730 | GO:0031429 |
| is_a | GO:0072588 | GO:0031429 |
| is_a | GO:1902494 | GO:0031429 |
| part of | GO:0031981 | GO:0031429 |
| part of | GO:0005575 | GO:0031429 |
| is_a | GO:1990904 | GO:0031429 |
| part of | GO:0005622 | GO:0031429 |
| part of | GO:0110165 | GO:0031429 |
| part of | GO:0031974 | GO:0031429 |
| part of | GO:0005634 | GO:0031429 |
| part of | GO:0043231 | GO:0031429 |
| part of | GO:0043232 | GO:0031429 |
| part of | GO:0043233 | GO:0031429 |
| is_a | GO:0005575 | GO:0031429 |
| part of | GO:0043226 | GO:0031429 |
| part of | GO:0043227 | GO:0031429 |
| part of | GO:0043228 | GO:0031429 |
| is_a | GO:0032991 | GO:0031429 |
| part of | GO:0043229 | GO:0031429 |
| part of | GO:0070013 | GO:0031429 |
| is_a | GO:0005732 | GO:0031429 |
