WormMine: GOTerm GO:0033192 calmodulin-dependent protein phosphatase activity GO

• Namespace: molecular_function
• Obsolete: false
• Description: Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.

0 Cross References

1 Data Sets

• GO Annotation data set

1 Ontology

• Name: GO

10 Ontology Annotations

11 Parents

Identifier	Name	Description
GO:0003674	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787	hydrolase activity	Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0016788	hydrolase activity, acting on ester bonds	Catalysis of the hydrolysis of any ester bond.
GO:0140096	catalytic activity, acting on a protein	Catalytic activity that acts to modify a protein.
GO:0016791	phosphatase activity	Catalysis of the hydrolysis of a phosphoric monoester, releasing a phosphate.
GO:0042578	phosphoric ester hydrolase activity	Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
GO:0004721	phosphoprotein phosphatase activity	Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cellular proteins and thereby provide an important mechanism for regulating cellular activity.
GO:0004722	protein serine/threonine phosphatase activity	Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions.
GO:0033192	calmodulin-dependent protein phosphatase activity	Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.

10 Relations

Relationship	Parent Term . Identifier	Child Term . Identifier
is_a	GO:0004723	GO:0033192
is_a	GO:0042578	GO:0033192
is_a	GO:0003674	GO:0033192
is_a	GO:0016787	GO:0033192
is_a	GO:0016791	GO:0033192
is_a	GO:0140096	GO:0033192
is_a	GO:0003824	GO:0033192
is_a	GO:0004722	GO:0033192
is_a	GO:0016788	GO:0033192
is_a	GO:0004721	GO:0033192

4 Synonyms

• Name: calcineurin activity
• Type: synonym

• Name: Ca2+/CaM-dependent protein phosphatase activity
• Type: synonym

• Name: calcium/calmodulin-dependent protein phosphatase activity
• Type: synonym

• Name: calcium- and calmodulin-dependent protein phosphatase activity
• Type: synonym